The common acid related diseases of the upper GI tract could be considered as primarily due to the defect in barrier function either of the gastric mucosal or duodenal epithelium leading to the formation of gastric or duodenal ulcers. An attempt was made in this chapter to discuss the history of peptic ulcer disease in humans and methods for the production of acute gastric lesions and ulcers in...

The recalcitrant oral ulceration (OU) and genital ulceration (GU) of Behçet disease (BD) can be very distressing and no standard therapy has been established yet. To determine the efficacy of Wet-cupping (W-C) as adjuvant treatment of oral and genital ulceration of BD, 24 patients were included in this prospective and comparative study. All patients included in the study had a recalcitrant oral...

BACKGROUND Genital ulcers (GU) are associated with an increased risk of HIV transmission. Understanding risk factors for genital ulcers and sexual behaviour patterns after onset of symptoms and health seeking behaviour among GU-patients can provide useful information to aid design effective prevention strategies for genital ulcers. We investigated risk factors of self-reported GUs and care-seek...

The aim of this study was to evaluate the healing effect an orabase ointment based on Libidibia ferrea L. induced mouth ulcers in rats. This is experimental "in vivo", descriptive, quantitative using model animals were divided into 3 groups: Group I (test), II (negative control) and III (positive control), evaluated periods 1, 5 10 days after ulcerative induction. Regarding diameter ulcers, pos...

this study aimed to estimate the rate of pressure ulcers in intensive care units (icus) and medical and surgical wards of iranian hospitals and compare the performance of methods of medical record review as well as direct observation for their detection.the research team visited 308 patients in medical and surgical wards of hospitals affiliated with tehran university of medical sciences and a f...

The effects of cimetidine on the healing and recurrence of duodenal ulcers and gastric ulcers were compared. The extent of the acid secreting areas was examined by the endoscopic Congo red methylene blue test. Using the extent of acid secreting areas gastric ulcers were classified into ulcers with and without extensive acid secreting areas. Duodenal ulcers were all associated with extensive aci...

This paper briefly reviews the authors' experimental and clinical use of lasers over a 20-year period, during which laser effects on 15 biological systems were studied. Low-energy laser radiation was found to have a stimulating effect on cells, and high-energy radiation had an inhibiting effect. The application of lasers to stimulate wound healing in cases of nonhealing ulcers is recommended.

Experimental evidence was provided to demonstrate the relationship between blood sugarlevel and stress-induced gastric ulcers in the albino rat; the stress employed being emotional (restraint) (i), In this paper are reported the results of experiments to demonstrate theinfluence of blood sugar level on volume of gastric contents, acidity and ulcer production In the stomach of the albino rat fol...

OBJECTIVE To evaluate pathogenesis and clinical features of lower limb ulcers in systemic sclerosis (SSc) and to propose a classification that could be used in clinical practice. METHODS Charts of 60 patients with SSc who had lower limb cutaneous lesions were reviewed. All patients had videocapillaroscopy and arterial and venous lower limb color Doppler ultrasonography (US). Arteriography was...

BACKGROUND Although healthcare quality has considerably improved in many countries, pressure ulcer is still a major health challenge worldwide. OBJECTIVES The current study aimed to evaluate the effects of TWOT on the healing of pressure ulcers. PATIENTS AND METHODS This study was a randomized controlled trial, and the convenient sample including 100 patients hospitalized in two university-...