Objectives: Nigella sativa is a medicinal plant that has long been used in traditional medicine for treating various conditions. Numerous animal studies provided evidences that the seed may elicit a broad anti-inflammatory/anti-oxidant activity. The aim of the present clinical trial was to evaluate anti-inflammatory and antioxidant properties of Nigella sativa oil in patients with rheumatoid ar...

a recent randomized clinical trial showed buspirone efficacy in the treatment of attention-deficit/hyperactivity disorder (adhd) in children. however, results from a recent multi-site controlled clinical trial of transdermal buspirone failed to separate it from placebo in a large sample of children with adhd. therefore, due to these inconsistent findings, this study was designed to assess the e...

For right-censored data perhaps the most commonly used tests are weighted logrank tests, such as the logrank and Wilcoxon-type tests. In this paper we review several generalizations of those weighted logrank tests to interval-censored data and present an R package, interval, to implement many of them. The interval package depends on the perm package, also presented here, which performs exact an...

The Modular Optical Experimental Instruments (MOEI) are newly-designed laboratory demonstration tools which integrate a whole set of optical devices on single board. instructors can easily bring the MOEI to classrooms and demonstrate phenomena projector screens. In order investigate impact instruction double-slit experiment, we investigated 134 undergraduate students with an open-ended experime...

Background: A decreased rate of successful helicobacter pylori (H.pylori) infection treatment has revealed serious demand for more effective regimens to eradicate infection. Therefore, probiotics have recently been considered to increase the rate of antibiotic regimens efficacy in H. pylori infections. In current randomized controlled trial, we evaluated the effect of double strain probiotic co...

background: depression is one of the most debilitating disorders during pregnancy and its recovery and treatment are among the concerns of obstetrics and gynecology experts. the present study aimed to determine the effect of omega-3 supplement on mild depression during pregnancy among primiparous women. method: in this double-blind clinical trial, 80 primiparous women were randomly divided into...

abstract introduction : conjugated linoleic acid (cla) has been shown to positively influence on calcium and bone metabolism in experimental animals and cell culture, but there are limited human data available. material and methods : this double-blind, placebo-controlled trial study was done on 76 healthy post-menopausal women (aged 55.1) which randomly assigned to receive daily four cla capsul...

selective estrogen receptor modulators (serms) such as raloxifene have already shown beneficial effects on negative, positive and general psychopathology symptoms in postmenopausal women with schizophrenia. the purpose of the present investigation was to assess the efficacy of raloxifene as an adjuvant agent in the treatment of men with chronic schizophrenia in an 8-week double-blind and placeb...