A convenient synthesis of novel bi/tricyclic azasugars fused thiazolidin-4-one and thiazinan-4-one by the one-pot tandem Staudinger/aza-Wittig/cyclization reaction under microwave radiation was demonstrated. The reactions were carried out with the azidosugar 1 and mercaptan acids via a key intermediate Schiff base and stereoselectively afforded the titled bi/tricyclic azasugars in good yield. A...

extended release formulation of alfuzosin, an a-antagonist used for prostatic hypertrophy, is available in market. it is convenient for older patients to take only one tablet a day. marketed alfuzosin formulation is three layered geomatrix tablet that requires special facilities, high cost, more time and complex operation than normal direct compression formulation. therefore, a less complicated...

Organic compounds containing thiourea function find many industrial, agricultural, pharmaceutical and analytical applications. Consequently, convenient, reliable, rugged and cost-effective methods for ensuring the quality of commercial products based on it are highly desirable. The case with which hydrogen peroxide in the presence of an excess of sodium hydroxide oxdatively desulphurise the thi...

Allicin, an extract from garlic, has been shown to be a systemic and pulmonary arterial vasodilator that acts by an unknown mechanism. In the present experiments, pulmonary vascular responses to allicin (10-100 microg), allyl mercaptan (0.3-1 mg), and diallyl disulfide (0.3-1 mg) were studied in the isolated lung of the rat under constant-flow conditions. When baseline tone in the pulmonary vas...

The adsorption of sodiumdodecyl sulfate (SDS) on gold surfaces coveredwith self-assembledmonolayers (SAMs) of thiols made with either hexadecyl mercaptan or 2-aminoethanethiol hydrochloride was investigated by probing the surface charge. This was accomplished by determining the force between a modified (with a negatively charged silica sphere) tip of an atomic forcemicroscope and the surface as...

nanocrystalline magnesium oxides were prepared by sol–gel method and were characterized by x-ray diffraction, n2-bet, sem and infrared spectroscopy techniques. the results confirmed the formation of nano- mgo materials with crystallite size in range of 5-20 nm and surface areas of 336-556m2/g. the product has been tested as destructive adsorbent for the decontamination of (2-chloroethyl) ethyl ...

abstract little information is available concerning morphological responses of lolium perenne cultivars (numan and speedy green) to salinity and trinexapac-ethyl treatment in initial growth. in order to evaluate the effect of salinity treatment (0, 2000, 4000 and 6000 mg/lit) and trinexapac-ethyl levels (0, 50, 100 gr/ha) on morphological responses of 'numan' and 'speedy green' in initial growt...

bermudagrass [cynodon dactylon (l.) pers.] is a perennial grass and has been long used as a medicinal herb in iranian traditional medicine to treat varied ailments. different parts of bermudagrass such as leaves, stolons, rhizomes and culms are rich sources of metabolites such as proteins, carbohydrates, mineral constituents, β-sitosterol, flavonoids, alkaloids, glycosides and triterpenoides. g...