Indocarbazostatins C (3) and D (4), new inhibitors of NGF-induced neurite outgrowth were isolated from culture broth of a mutant strain, Streptomyces sp. MUV-6-83. The structural elucidation of 3 and 4 revealed that these inhibitors were methyl ester analogs of the corresponding ethyl ester compounds, indocarbazostatin (1) and indocarbazostatin B (2), respectively.

Arabian deep-sea red shrimp Aristeus alcocki is considered to be an ideal source of pigments, especially astaxanthin, and its analogs. Extraction pigments from exoskeleton discards A. was analyzed by using organic solvents, namely, n-hexane, acetone, ethyl acetate, methanol, ethanol under cold hot conditions. A significantly greater yield obtained acetone: methanol (1:1 v/v) (10.4-10.9%) (9.3-9...

An arylrhodium(I) species selectively reacts with the cyano group of ethyl cyanoformate to afford the corresponding alpha-keto ester in good yield.

Biodiesel fuels consist of a mixture different fatty acid esters. The thermophysical properties the esters are decisive for combustion and storage. Especially density viscosity influence, e.g., energy density, spray quality lubrication in diesel engine. For some esters, several studies on can be found literature wide pressure reasonably temperature range. However, data at high pressures as well...

Synthesis of novel neuraminidase inhibitor -- carborane ester of oseltamivir carboxylic acid is described, and its physicochemical and spectral characteristics is provided. Surprisingly, carborane analog of oseltamivir is of an order of magnitude less active than its precursor, the corresponding ethyl ester, which is the active principle of pharmaceutical preparations used in influenza prophyla...

Conformational factors in self-assembled chiral tetraamide macrocycles control their gas-phase enantioselectivity towards the ethyl ester of naphthylalanine to levels typical of enzymes.

The alkaline hydrolysis of C-4 to C-8 (butanoate to octanoate) ethyl esters shows autocatalytic kinetics when performed under two-phase conditions without any mixing solvent. Alkanoate anions and ethanol are the products of the reaction. A dynamic model is proposed that describes quantitatively this kinetic behavior. The model includes the main processes occurring in the biphasic medium and the...

Five field experiments were conducted in Ontario to determine the tolerance of dry beans pyraflufen-ethyl (6.7 and 13.4 g ai ha-1), 2,4-D ester (520.3 1040.6 ha-1) pyraflufen-ethyl/2,4-D (527 1054 applied preplant. Pyraflufen-ethyl at 6.7 ha-1 caused < 2% injury azuki, kidney, small red, white bean. 520.3 up 4 6% azuki bean; 5 12% kidney 7 red 8% bean, respectively. Pyraflufen-ethyl/2,4-...

The reaction of ethyl benzoylacetate with formaldehyde and natural amino acid ester hydrochlorides in acetate buffer (AcONa/AcOH, pH 4.0) at room temperature afforded 41–61% new 5-benzoylhexahydropyrimidine derivatives. synthesized compounds were evaluated for their vitro cytotoxic activity against normal (HEK293) tumor cell lines (Jurkat, HepG2). T-Lymphoblastic leukemia Jurkat cells turned ou...