In March 2012 Henry et al. published a paper that explored whether or not the consumption of thiamethoxam via nectar could be a causal factor of Colony Collapse Disorder (CCD) in honeybees. In the first part of their report, Henry et al. (2012) measured the homing success after “ecologically relevant” thiamethoxam exposure and compared it to non-thiamethoxam exposed, control homing rates [see G...

Heart failure constitutes a major health problem with a current prevalence of over 5.8 million in the USA and over 23 million worldwide. (Lloyd-Jones, 2010) During the last decades a dramatic increase in the number of heart failure patients and hospitalizations was observed (Curtis et al., 2008) with an incidence of more than 550,000 annually in the USA and a lifetime risk of 20%. Although prev...

The Eustachian tube (ET) is a narrow canal that courses from the middle ear cavity to the nasopharynx, which opens to provide ventilation to the middle ear and to equalize middle ear and ambient pressures (1). In this article, we refer by “Eustachian tube dysfunction” only to obstructive ET dysfunction, i.e., failure to open and ventilate the middle ear, as opposed to patulous ET dysfunction, i...

Increased expression of endothelin (ET)–1 has been well described in heart failure and has been thought to potentiate the progression of this disorder through hemodynamic effects as well as vascular and cardiac remodeling.1,2 Investigations of heart failure animal models3,4 as well as early clinical studies5–7 supported a potential beneficial effect of ET-1 blockade in heart failure. On the bas...

background: renal complication of leptospirosis is common and its clinical manifestations vary from urinary sediment changes to acute renal failure. the aim of this study was to determine the final outcome of renal involvement in leptospirosis. methods: this longitudinal prospective study included all serologically confirmed cases of leptospirosis with evidence of renal failure. all patients we...

1 Sin et al. American Journal of Respiratory Critical Care Medicine; 1999 2 Lafranchi et al. Circulation; 1999 3 Philippe et al. Heart; 2005 4 Javaheri et al. Circulation; 1998 5 Sin et al. American Journal of Respiratory Critical Care Medicine; 1999 Sleep-disordered breathing (SDB) is recognized as a serious health problem that impacts the cardiovascular system. Clinical studies have shown the...