This study describes recent trends in incidence, survival and prevalence of subgroups of esophageal and gastric cancer in Linzhou city between 2003 and 2009. Data of esophageal and gastric cancer for the period of interest were extracted from the Linzhou Cancer Registry. Using information on tumor morphology or anatomical site, data were divided into six groups; esophageal squamous cell carcino...

OBJECTIVES Increasing evidence showed that microRNAs (miRNAs) were implicated in the chemical resistance of human cancers. We intended to investigate the role of miR-218 in cisplatin sensitivity of esophageal cancer cells. METHODS Quantitative real-time polymerase chain reaction (qRT-PCR) was carried out to analyze miR-218 expression in human esophageal cancer cell line Eca9706 and a cisplati...

background : esophageal cancer is the 7th most common cancer in iran. the northern part of the country shows the highest incidence for this malignancy. in this study we present some epidemiological and clinicopathological characteristics of patients with esophageal carcinoma in this region. methods : in a cross sectional study, 238 esophageal cancer patients were enrolled in a prospective study...

Orthotopic models of various types of tumors are widely used in anti-tumor therapeutic experiments in preclinical studies. However, there are few ways to appropriately monitor therapeutic effect in orthotopic tumor models, especially for tumors invisible from the outside. In this study we aimed to establish a non-invasive semi-quantitative bioluminescent imaging method of monitoring an orthotop...

Radiotherapy is one of the most important treatments for esophageal cancer, but radioresistance remains a major challenge. Previous studies have shown that microRNAs (miRNAs or miRs) are involved in human cancers. miR-124 has been widely reported in various cancers and it is intimately involved in proliferation, cell cycle regulation, apoptosis, migration, and invasion of cancer cells. The aim ...

objective: the objective of this study was to investigate inhibition and anti-cancer effects of linoleic acid on the mcf-7 and mda-mb-231 human breast cancer cells. materials and methods: cell lines human breast cancer mcf-7 (gdc055) and mda-mb-231 (htb-26) cell lines were obtained from atcc. mcf-7 estrogen receptor positive human breast cancer cell line and  the estrogen receptor negative huma...

Squamous cell carcinomas of esophagus are responsible for more than 80% of esophageal malignancies in Turkey. Idiopathic portal hypertension is a rare underlying cause of esophageal variceal bleeding. In such cases, detection of concomitant esophageal squamous cell cancer is also a rare occurrence. We report an unusual case of bleeding esophageal varices secondary to idiopathic portal hypertens...

background: esophageal cancer is often diagnosed in the last stages where the chance of patient’s survival is very low. the aim of this systematic review was presentation of valid estimation of survival in patients with esophageal cancer in different regions of iran. methods: a systematic review was carried out based on the reliable domestic medical databases including: sid, magiran, irandoc an...