Erythromelalgia is a rare syndrome that is characterized by episodic attacks of burning pain, erythema, and increased temperature usually affecting the extremities, which is aggravated by warmth or exercise. We describe a patient with a 3-year history of refractory burning pain and red ears. A review of clinical features, disease classification, associated diseases, and treatment of this diseas...

Acknowledgement: We appreciate comments and suggestions from the reviewers and from participants of the SEJ Special Issue conference at Temple University in April 2010. Zoltan Acs provided highly useful suggestions. We appreciate careful editing by Tamzin Mitchell.