Pharmacological inhibitors of cysteine proteases have provided useful insights into the regulation of calpain activity in erythrocytes. However, the precise biological function of calpain activity in erythrocytes remains poorly understood. Erythrocytes express calpain-1, an isoform regulated by calpastatin, the endogenous inhibitor of calpains. In the present study, we investigated the function...

magnesium (mg) is the second most abundant intracellular cation and is involved in numerous physiological functions, including protein folding, intracellular signaling and enzyme catalysis. it has been shown that magnesium deficiency exacerbates pulmonary airways hyperreactivity. several studies suggest that magnesium level has no effect on asthma but others had shown a contributory effect. bec...

The pathological changes of erythrocytes were detected at the nanometer scale, which was important for revealing the onset of diseases, early diagnosis, and effective therapies. Diseases may disturb the morphology and function of erythrocytes at molecular scale. There were dramatic surface deformations in topography of erythrocytes from a patient with elliptocytosis complicating idiopathic thro...

i read with interest dr. yazdani's reply about the article entitled “administration of magnesium sulfate to women with premature labor: the effect on bleeding time”. 1 in my review of hematology references, i could not find any reference for determining hemoglobin (hb) sooner than 24 hrs and dr. yazdani had not cited any reference either. however, about the influence of hb on homeostasis, there...

Background: Morphological examinations of urinary erythrocytes can be of diagnostic value in initial evaluation of hematuria. Dysmorphic urinary red blood cells are known to indicate a glomerular origin of bleeding. We examined the clinical usefulness of this test in a population complained of hematuria by use of three different methods: light microscopy, phase contrast microscopy, and Wright s...

background: morphological examinations of urinary erythrocytes can be of diagnostic value in initial evaluation of hematuria. dysmorphic urinary red blood cells are known to indicate a glomerular origin of bleeding. we examined the clinical usefulness of this test in a population complained of hematuria by use of three different methods: light microscopy, phase contrast microscopy, and wright s...

background: in recent years, the widespread use of microwave producing instruments specially mobile phones; result in growing concern regarding the possible effects associated with these waves on human health. in the present study investigated the genotoxic effects of mobile phone radiation in adult mice (balb/c) and their embryos. methods: in this experimental research pregnant mice were irrad...

Global warming implies the risk of a changing oxygen regime in seas and oceans our planet. The mitochondrial complex nuclear erythrocytes cartilaginous fish, as energy basis blood cells, has repeatedly encountered such climatic fluctuations throughout their evolutionary history. In this regard, features adaptive strategy erythrocyte thornback ray (Raja clavata L.) are interest from ecological p...

Broiler chickens are birds that grow very fast, but have low body resistance and easily stressed. This study aimed to examine the effect of nucleotide turmeric extract (Curcuma longa Linn) on blood profile (erythrocytes, hemoglobin leukocytes) carcass production (weight carcass, weight breast, thighs wings) in broiler chickens. Data was collected using a completely randomized design with 7 trea...

Despite the small number of leukocytes relative to erythrocytes in the circulation, leukocytes contribute significantly to organ blood flow resistance. The present study was designed to investigate whether interactions between leukocytes and erythrocytes affect the pressure-flow relationship in a hemodynamically isolated rat gracilis muscle. At constant arterial flow rate, arterial pressure was...