Correspondence to Professor Leonardo Punzi; [email protected] Osteoarthritis (OA), a disease that mainly targets cartilage, also affects ligaments, the subchondral bone and synovium, and, according to recent definitions, it is a disease of the joint as an organ. Its most characteristic radiographic features are joint space narrowing, bone sclerosis and osteophytes; bone erosions, and in particu...

Erosive lichen planus is an uncommon variant of lichen planus. Chronic erosions of the soles, accompanied by intense and disabling pain, are some of its most characteristic manifestations. We present the case of a woman who developed oral and plantar erosive lichen planus associated with lichen planus pigmentosus and ungueal lichen planus that were diagnosed after several years. The patient fai...

Background and Aim: Lichen planus is an inflammatory autoimmune mucocutaneous disease. Stimulation of T cells and antigen-presenting cells (APCs), such as dendritic cells, mediates apoptosis of keratinocytes and basement membrane destruction. The aim of this study was to investigate the expression of one of the immune cell markers (CD86) in erosive oral lichen planus. Materials and Methods: In...

was limited to children with an erosive peripheral arthritis in addition to ankylosing spondilitis. Although we did not ascertain the extent of erosive disease in all our patients, they were biased towards those with more severe disease and hence were also likely to be erosive. The inclusion of patients that had already had joint replacement helps support this conclusion. Another similarity was...

conclusions since ki-67 is extensively accepted as an important biomarker in diagnosis, prognosis and treatment of cancerous and precancerous lesions, a high degree of presence of this biomarker in chronic precancerous lesions, such as erosive olp, can be of great use in prognosis and suggested treatments. objectives this study aimed to evaluate ki-67 expression in erosive and non-erosive oral ...

Information on sediment and nutrient export from catchments and about related erosive processes is required by catchment managers and decision-makers. Many models exist for the consideration of these processes. However, these models differ greatly in terms of their complexity, their inputs and requirements, the processes they represent and the manner in which these processes are represented, th...