Previous work from this laboratory demonstrated that 17-beta estradiol (E2) can directly stimulate the transcription rate of the rat luteinizing hormone beta (LH beta) gene and that an upstream portion of the LH beta gene between -2.0 and -0.6 kilobases could confer an E2-stimulated response to a reporter gene in transient expression assays. To localize the LH beta estrogen response element (ER...

Two N otre Dame s tu d en ts w ere robbed a t gun point as they m ade their way back to campus early Saturday m orn­ ing, according to Charles Hur­ ley, assistant director of Notre Dame Security. Two male students reported th ey w ere w a lk in g back to cam pus on Eddy S treet, ju s t so u th of th e five p o in ts intersection, when they w ere approached by two men, who dem an d ed th e ir m ...

We present low-dispersion visible spectra of two regions of the 30 Doradus nebula. When corrected for atomic continuum emission and divided by the spectrum of the exciting and illuminating stars, one of the two spectra clearly shows Extended Red Emission (ERE) superimposed on the scattering component. This ERE band peaks around 7270Å and is 1140Å width. HAC grains are found to explain the obser...

Estrogens exert their regulatory potential on gene expression through different nuclear and non-nuclear mechanisms. A direct nuclear approach is the interaction of estrogen with specific target sequences of DNA, estrogen response elements (ERE) or units. EREs can be grouped into perfect and imperfect palindromic sequences with the imperfect sequences differing from the consensus sequence in one...

Because concern over endocrine disrupting reactions caused by chemicals to humans and animals is growing, a rapid and reliable screening assay for endocrine disrupting chemicals is required. We have developed an in vitro screening assay based on a hormone receptor mechanism using a surface plasmon resonance (SPR) sensor. The interaction between an estrogen receptor alpha (ER) and an estrogen re...

1 ABSTRACT In this paper we propose a new line search algorithm that ensures global convergence of the Polak-Ribi ere conjugate gradient method for the unconstrained minimization of nonconvex diierentiable functions. In particular, we show that every limit point produced by the Polak-Ribi ere iteration is a stationary point of the objective function. Moreover, we prove that, asymptotically, the...

Received: 27. 02. 2006. Accepted: 08. 06. 2006. The aim of this study �as to recognize differences in midterm clinical outcome after femoral neck fracture and hip endoprosthesis implantation. A total of 145 patients �ere examined, 32 patients �ith unipolar, 70 �ith bipolar and 43 patients �ith total hip endoprosthesis. The mean values of Harris Hip Score, after 3.8 ± 1.9 years, �ere: 72.1 ± 17....

the date of receipt and acceptance should be inserted later Abstract. Possible forsterite nanoparticle model of the Extended Red Emission(ERE) is proposed on the basis of photo-luminescence of forsterite after gamma-ray and neutron irradiation. Forsterite exhibits interesting thermoluminescence spectrum similar to ERE of Red Rectangle after irradiation in low temperature. It is shown that the f...

Results: A total of 85 subjects (31 female and 54 male) with a mean age of 35.1 ± 11.4 years were enrolled. Th ere was no signifi cant diff erence between the groups in terms of mean age, height, or body weight (P > 0.05). Th e mean body mass index (BMI) of the participants was 26.55 kg/m2. While the BMR was found to be lower, resistance was higher in patients in the inactive group (P < 0.05 fo...