Psychogenic non-epileptic seizures (PNES) need to be differentiated from epileptic seizures as the management varies for both. Presence of tongue biting, falling and urinary incontinence favors a diagnosis of epileptic seizures. We report two children with features suggestive of epileptic seizures that were eventually diagnosed as PNES with the help of video-EEG monitoring.

PURPOSE We aimed to define the characteristics of epileptic nystagmus and correlate those with other clinical findings in a large number of patients. METHODS We report a patient with epileptic nystagmus and additionally reviewed the reported clinical features of 36 more patients through a systematic literature search. We analyzed the characteristics of epileptic nystagmus and attempted correl...

Valproic acid is widely used as an anti-epileptic globally. Anti-epileptic action is mediated by Gamma Amino Butyric Acid (GABA) receptors. In past and recently, several other clinical outcomes have been proposed by various studies. These under-reported clinical actions apart from anti-epileptic activity are mediated by various intracellular and extracellular pathways. Several mechanisms like H...

Objective: To identify the utilization pattern of antiepileptic drugs (AEDs) in a representative sample of the Pakistani population. To highlight the main risk factors associated with different forms of epilepsy. Methods: A retrospective drug utilization review study was conducted at three teaching institutions of Karachi. During the nine months study period, epileptic and non-epileptic patient...

The term “total intravenous anesthesia” refers to the preservation of an anesthetic plane with use injectable anesthetic, a sedative that is often given in intermittent boluses. tendency have recurrent unprovoked seizures known as epilepsy. Its prevalence ranges from 0.5% 1%. highest incidence rates are those anatomical or developmental brain abnormalities, well at extremes age. most common tri...