نتایج جستجو برای: enzymatic prehydrolysis

تعداد نتایج: 55006  

2016
Piotr Minkiewicz Małgorzata Darewicz Anna Iwaniak Justyna Bucholska Piotr Starowicz Emilia Czyrko

Internet databases of small molecules, their enzymatic reactions, and metabolism have emerged as useful tools in food science. Database searching is also introduced as part of chemistry or enzymology courses for food technology students. Such resources support the search for information about single compounds and facilitate the introduction of secondary analyses of large datasets. Information c...

1995
De Witt Sumners

ne of the important issues in molecular biology is the three-dimensional structure (shape) of proteins and deoxyribonucleic acid (DNA) in solution in the cell and the relationship between structure and function. Ordinarily, protein and DNA structure is determined by X-ray crystallography or electron microscopy. Because of the close packing needed for crystallization and the manipulation require...

Journal: :The Journal of biological chemistry 2007
Céline Schalk-Hihi Hong-Chang Ma Geoffrey T Struble Shariff Bayoumy Robyn Williams Eric Devine Ioanna P Petrounia Tara Mezzasalma Lee Zeng Carsten Schubert Bruce Grasberger Barry A Springer Ingrid C Deckman

A parallel approach to designing crystallization constructs for the c-FMS kinase domain was implemented, resulting in proteins suitable for structural studies. Sequence alignment and limited proteolysis were used to identify and eliminate unstructured and surface-exposed domains. A small library of chimeras was prepared in which the kinase insert domain of FMS was replaced with the kinase inser...

2014
Yuki Goto Yuki Niwa Takehiro Suzuki Shiho Uematsu Naoshi Dohmae Siro Simizu

Hyaluronidase1 (HYAL1) is a hydrolytic enzyme that degrades hyaluronic acid (HA) and has three predicted N-glycosylation sites at Asn(99), Asn(216), and Asn(350). In this report, we show the functional significance of N-glycosylation on HYAL1 functions. Using mass spectrometry, we demonstrated that HYAL1 was N-glycosylated at the three asparagine residues. N-glycosylation of HYAL1 is important ...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2008
Maite Roca Benjamin Messer Donald Hilvert Arieh Warshel

Elucidating the relationship between the folding landscape of enzymes and their catalytic power has been one of the challenges of modern enzymology. The present work explores this issue by using a simplified folding model to generate the free-energy landscape of an enzyme and then to evaluate the activation barriers for the chemical step in different regions of the landscape. This approach is u...

2017
Neshat Golikhajeh Bahram Naseri Jabraeil Razmjou

Digestive enzymatic activity in three geographic strains (Miandiab, Kalposh and Moghan regions) of Spodoptera exigua (Hübner) (Lepidoptera: Noctuidae) reared on different sugar beet cultivars (Dorothea, Rozier, Persia and Perimer) was studied under laboratory conditions (25 ± 1 °C, 65 ± 5% RH, and a photo period of 16:8 (L:D) h photoperiod). The results of this study demonstrated that digestive...

Solmaz Pourgonabadi Zahra Tayarani-Najaran

Considering the ease of isolation and high expansion potential of pulp stem/progenitor cells isolated from wisdom and primary teeth they have been implicated as the most reliable autologous cell source in dental tissue engineering. Meanwhile, different isolation methods have remarkable impacts on the expansion potential of adult stem cells. In enzymatic digestion method extracted teeth as denta...

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