BACKGROUND This study evaluated the clinical and economic impact of the emergence of third-generation cephalosporin-resistant Enterobacter species. METHODS Mortality, length of hospitalization, and hospital charges were examined in a cohort that was selected from a group of 477 patients with initial cultures that yielded a third-generation cephalosporin-susceptible Enterobacter species. Case ...

Skinner (1928) tested 23 strains of Bacteriumn aerogenes (Aerobacter aerogenes) and reported that two, and possibly a third, assimilated gaseous nitrogen when cultured in liquid medium, a claim confirmed 27 years later by Hamilton and Wilson (1955) using the N" isotopic method. Their experiments indicated that A. aerogenes incorporated significant amounts of tracer and that anaerobically, in a ...

During a Spanish surveillance study, two natural variants of DHA β-lactamases, DHA-6 and DHA-7, were found, with the replacements Ala226Thr and Phe322Ser, respectively, with respect to DHA-1. The DHA-6 and DHA-7 enzymes were isolated from Escherichia coli and Enterobacter cloacae clinical isolates, respectively. The aim of this study was to genetically, microbiologically, and biochemically char...

The Enterobacter cloacae complex is genetically very diverse. The increasing number of complete genomic sequences of E. cloacae is helping to determine the exact relationship among members of the complex. E. cloacae P101 is an endophyte of switchgrass (Panicum virgatum) and is closely related to other E. cloacae strains isolated from plants. The P101 genome consists of a 5,369,929 bp chromosome...

In the course of the studies presented in the preceding paper it was observed that Aerobacter aerogenes could grow on histidine as the sole source of carbon and nitrogen (1). The nature of the microbial enzymes responsible for the complete degradation of histidine was not known and appeared therefore to be an appropriate subject for investigation. After initiation of these studies, the results ...

It has previously been reported that a capsulated strain of Aerobacter aerogenes, 1033, can utilize glycerol as sole source of carbon and of energy (l), and that glycerol induces this organism to form a diphosphopyridine nucleotide-linked glycerol dehydrogenase (2). This enzyme may be identical with the glycerol dehydrogenase discovered by Burton and Kaplan (3) in another strain of A. aerogenes...

Enterobacter aerogenes IFO 12010 contains a carbon-phosphorus (C-P) bond cleavage enzyme catalyzing the liberation of inorganic phosphate from various alkyl- and phenylphosphonic acids. The enzyme in the bacterium was found to be composed of two physically different protein components, E2 and E3. The molecular weights of E2 and E3 were 560,000 and 110,000, respectively, and E3 was resolved into...

Neely, W. Brock (The Dow Chemical Co., Midland, Mich.). Action of formaldehyde on microorganisms. III. Bactericidal action of sublethal concentrations of formaldehyde on Aerobacter aerogenes. J. Bacteriol. 86:445-448. 1963.-Bacteriostatic concentrations of formaldehyde were found to be bactericidal during the initial growth period. This bactericidal activity was due to the primary induction of ...