An algorithm for non-intrusively coupling a commercial finite element software with a research code implementing a hierarchical enrichment of finite element spaces is presented. Examples of hierarchical methods supported by the algorithm are the Generalized or eXtended FEM (GFEM), the scale-bridging GFEM with numerically defined enrichment functions (GFEMgl), and the p-version of the FEM. The p...

A method is introduced for estimating the contribution of gluconeogenesis to glucose production. 2H20 is administered orally to achieve 0.5% deuterium enrichment in body water. Enrichments are determined in the hydrogens bound to carbons 2 and 6 of blood glucose and in urinary water. Enrichment at carbon 6 of glucose is assayed in hexamethylenetetramine, formed from formaldehyde produced by per...

Microfluidic system is widely employed in the detection of environmental contaminants and biological specimens. One of the critical issues which limits the applications of microfluidic chips is the limit of detection of trace specimens. Liquid–liquid extraction is of great importance in the preprocessing in microfluidic devices. In this paper, we developed a real-time fluorescence detection mic...

Although PM was basically created to treat subjective comparisons, given exact values can be converted to Potential Method flow. A new feature of PM is a parameter called FlowNorm which helps to treat problems where each criterion has its own measurement scale. Complex hierarchial structures and problems modelled by decision tables can be handled. Incomplete data, such as incomplete belief, is ...

A key aspect of the Object-Oriented (OO) approach is that a designer can enrich an OO system by providing suitable (re-)definitions for some of the methods of the given system. Application frameworks provide good examples of such enrichment. An OO framework typically provides a number of template methods that implement specific patterns of calls to hook methods. An application developer can cus...

We are interested in the efficient and reliable numerical solution of parametric multi-scale problems, the multi-scale (parametric) character of which is indicated by ε (μ) if expressed in the general notation of (1). It is well known that solving parametric multi-scale problems accurately can be challenging and computationally costly for small scales ε and for a strong dependency of the soluti...

This paper presents an automatic method and interface to enrich semantically WordNet 1.6. with categories or classes from other classification systems. In order to build the WordNet enriched it is necessary the creation of a interface to label WordNet with categories from different available classification systems. We also describe features of the design and implementation of the interface to o...

In this part of the work, a notion of generalized enrichment is proposed to construct the global partition polynomials or to enrich global partition polynomial basis with extra terms corresponding to the higher order derivatives of primary variable. This is accomplished by either multiplying enrichment functions with the original global partition polynomials, or increasing the order of global p...

Gene set enrichment analysis for analyzing large profiling and screening experiments can reveal unifying biological schemes based on previously accumulated knowledge represented as "gene sets". Most of the existing implementations use a fixed fold-change or P value cutoff to generate regulated gene lists. However, the threshold selection in most cases is arbitrary, and has a significant effect ...

Although currently available strategies for the preparation of exome-enriched libraries are well established, a final validation of the libraries in terms of exome enrichment efficiency prior to the sequencing step is of considerable importance. Here, we present a strategy for the evaluation of exome enrichment, i.e., the Multipoint Test for Targeted-enrichment Efficiency (MTTE), PCR-based appr...