نتایج جستجو برای: endothelial cell antibodies

تعداد نتایج: 1859190  

Ali Ahmad Bayat Farzaneh Notash Haghighat Jafar Mahmoudian Mahmood Jeddi-Tehrani, Mahmood Shams Mohammad Reza Rezvani,

Background: Human CD34 is a transmembrane glycoprotein which is expressed in human hematopoietic stem cells (HSCs) and the small- vessel endothelial cells of a variety of tissues. CD34 plays a critical role as a marker for diagnosis and classification of leukemia. Anti CD34 antibodies are used for isolation and purification of HSCs from bone marrow, peripheral blood and cord blood. Objective: ...

Journal: :European Journal of Vascular and Endovascular Surgery 2006

Journal: :European journal of immunology 2018
Lisa K Blum Richard R L Cao Andrew J Sweatt Matthew Bill Lauren J Lahey Andrew C Hsi Casey S Lee Sarah Kongpachith Chia-Hsin Ju Rong Mao Heidi H Wong Mark R Nicolls Roham T Zamanian William H Robinson

Idiopathic pulmonary arterial hypertension (IPAH) is a devastating pulmonary vascular disease in which autoimmune and inflammatory phenomena are implicated. B cells and autoantibodies have been associated with IPAH and identified as potential therapeutic targets. However, the specific populations of B cells involved and their roles in disease pathogenesis are not clearly defined. We aimed to as...

Aghaei, Fariba , Alijani, Eidy , Jafari Sohi, Hadis, Sarshin, Amir ,

Background: Exercise and the simultaneous use of progenitor cells is a new strategy aimed for reducing diabetic disorders. One of the known mechanisms is angiogenic disorders caused by diabetes. Therefore, the present study was performed to determine the simultaneous effect of resistance training with endothelial progenitor cell injection on the expression of angiogenic factors in the skeletal ...

Objective: Envenomation by heamotoxic snakes constituted a critical health occurrence in the world. Bleeding is the most sever consequence following snake bite with viperid and crothalid snakes. It is believed that the degradation of vascular membrane caused hemorrhage; in contrast, some suggested that direct cytotoxicity has role in endothelial cell disturbances. This study was to evaluate the...

Journal: :The Journal of Experimental Medicine 1990
J L Platt G M Vercellotti B J Lindman T R Oegema F H Bach A P Dalmasso

Heparan sulfate proteoglycan associated with endothelial cells in normal blood vessels inhibits intravascular coagulation and egress of blood cells and plasma proteins, key features of hyperacute rejection. It was shown herein that exposure of cultured porcine endothelium to human serum as a source of natural antibodies and complement caused cleavage and release of 5% of endothelial cell proteo...

Journal: :The Journal of clinical investigation 1997
S Pillarisetti L Paka J C Obunike L Berglund I J Goldberg

Vessel wall subendothelial extracellular matrix, a dense mesh formed of collagens, fibronectin, laminin, and proteoglycans, has important roles in lipid and lipoprotein retention and cell adhesion. In atherosclerosis, vessel wall heparan sulfate proteoglycans (HSPG) are decreased and we therefore tested whether selective loss of HSPG affects lipoprotein retention. A matrix synthesized by aortic...

Journal: :The Israel Medical Association journal : IMAJ 2012
Laís V Lage Jozélio F de Carvalho Maria T C Caleiro Natalino H Yoshinari Licia M H da Mota Munther A Khamashta Wilson Cossermelli

BACKGROUND Antibodies directed against endothelial cell surface antigens have been described in many disorders and have been associated with disease activity. Since the most prominent histopathologic feature in mixed connective tissue disease (MCTD) is the widespread and unique proliferative vascular lesion, our aim was to evaluate the frequency of anti-endothelial cell antibodies (AECA) in thi...

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