Pentoxifylline was inactive when tested against 70 fresh clinical bacterial isolates, as well as when tested alone and in combination with erythromycin, vancomycin, or rifampin against Escherichia coli PC1349 (wild type) and its heptose-deficient outer membrane mutant E. coli PC2040. No antibacterial activity of pentoxifylline or its metabolites could be detected in sera from patients receiving...

The present study aimed to assess the occurrence of cytological endometritis (CYTO), a nonsymptomatic inflammation endometrium, at first artificial insemination (AI) postpartum in Norwegian Red cows. Further, risk factors for CYTO manifestation and its effect on reproductive success late embryo loss were evaluated. In total 1,648 cows located 116 herds included study. On mainly spontaneous estr...

PURPOSE pentoxifylline (PTX) and tocopherol (vitamin E) are antioxidants previously shown to be useful in combination in the treatment of late radiation induced toxicity. The purpose of this study was to investigate the benefit of combination therapy with carbogen pentoxifylline and tocopherol in the mitigation of late radiation effects. As the optimal duration of PTX and tocopherol treatment h...

Objective Despite numerous studies indicating an imperative role for reproduction, however, the role of Vitamin D supplementation on outcomes of assisted reproductive techniques remains controversial. Therefore, the objective of this clinical trial was to evaluate the effect of consumption of Vitamin D supplementation 6 weeks prior to ICSI on fertility indexes. MaterialsAndMethods The present s...

Background: The objective of this study was to compare the pregnancy rate of Frozen-thawed Embryo Transfer (FET) on natural versus hormone replacement therapy (HRT) cycle endometrium, in patients with repeated IVF failure (RIF). Materials and Methods: In this observational study, the pregnancy rate after FET on natural endometrium in patients with RIF and previously poor endometrium (<7mm) on H...

OBJECTIVE Prostaglandins (PGs) function in various reproductive processes, including luteolysis, maternal pregnancy recognition, conceptus development, and parturition. Our earlier study has shown that PG transporters ATP-binding cassette, subfamily C, member 4 (ABCC4) and solute carrier organic anion transporter family, member 2A1 (SLCO2A1) are expressed in the uterine endometrium in pigs. Sin...

Background Hysteroscopic adhesiolysis anatomically restores the uterine cavity in cases of Asherman's syndrome (AS); however, the extent of endometrial fibrosis could determine the pregnancy outcome. Objectives To determine whether endometrial thickness could influence pregnancy outcome of hysteroscopic adhesiolysis in women with a history of AS. Subjects and methods This was a retrospectiv...

background: sildenafil citrate may increase endometrial thickness and affect the outcome of frozen-thawed embryo transfer cycles. objective: the aim of this study was to estimate the effect of sildenafil citrate on ultrasonographic endometrial thickness and pattern and to investigate the estrogen level on the day of progesterone administration, the implantation rate and chemical pregnancy rate ...

Rats infected with the helminth Capillaria hepatica regularly develop septal hepatic fibrosis that may progress to cirrhosis in a relatively short time. Because of such characteristics, this experimental model was selected for testing drugs exhibiting antifibrosis potential, such as pentoxifylline, gadolinium chloride and vitamin A. Hepatic fibrosis was qualitatively and quantitatively evaluate...

Many species exhibiting hemochorial placentation experience an accumulation of macrophages in the endometrium during pregnancy. For the present study, it was tested whether macrophages also accumulate in the endometrium of the sheep, which is a species undergoing an epitheliochorial placentation. An additional objective was to determine whether regulation of endometrial macrophage number occurs...