BACKGROUND No data are currently available regarding kinetics of human endometrial steroid receptors in stimulated cycles. METHODS In 31 patients (age <39 years) stimulated with gonadotrophins and GnRH antagonists for intrauterine insemination (IUI) an endometrial biopsy was performed on the first day after the end of menstruation and a second biopsy was performed two (Group 0 + 2, n = 10) or...

For nearly 20 years, tamoxifen has been successfully used in the management of breast cancer. Tamoxifen is a mixed estrogen agonist/antagonist that has a proliferative effect on the endometrium. The drug has been associated with a higher percentage of endometrial polyps and hyperplasia than in control patients as well as slightly increased risk of endometrial cancer. Although patients need to u...

Background Even in the face of a substantial increase in the numbers of endometrial cancer cases and in the numbers of women who have risk factors, there is no clear agreement about the indications for assessing the endometria of women with abnormal bleeding or about the tools to use in that assessment. This study sought to determine in a group of high risk women with abnormal uterine bleeding,...

OBJECTIVE To assess the role of endometrial thickness on vaginal ultrasound assessment and menstrual history in predicting endometrial hyperplasia in women with polycystic ovary syndrome (PCOS) who presented with infertility due to anovulation. METHODS This was a prospective study in a university referral-based fertility and endocrine clinic. Fifty-six women with PCOS presenting with infertil...

BACKGROUND Genital tuberculosis (GTB) is an important cause of female infertility, especially in developing countries. The positive results of polymerase chain reaction (PCR) in endometrial GTB in the absence of tubal damage raise the possibility of the detection of sub-clinical or latent disease, with doubtful benefits of treatment. OBJECTIVE To evaluate the mycobacterium tuberculosis infect...

ABSTRACT Objective To describe the effect of the intermittent administration of vaginal progesterone and a low-dose estradiol patch on endometrial stability, as assessed by the rate of amenorrhea and endometrial stimulation. Methods This was an open study in which 64 moderately symptomatic, postmenopausal women were treated in the outpatient clinic of our University Hospital for different i...

Abnormal uterine bleeding (AUB) is responsible for 33% of all outpatient gynecologic visits, with the majority of cases just after menarche or in the perimenopausal period.1 Most cases are related to pregnancy, anatomic uterine pathology (fibroids, polyps, adenomyosis), anovulation, maladies of hemostasis, or neoplasia. Since evaluation of the endometrium is a key component in the diagnostic tr...

BACKGROUND Office hysteroscopy with endometrial biopsy is usually the first investigation for abnormal uterine bleeding and other uterine diseases. AIMS To evaluate the effect of oral drotaverine with mefenamic acid on pain perception during hysteroscopy and endometrial biopsy and to compare it with that of paracervical block using 1% lignocaine and with that of intravenous sedation using dia...

background: more than 40% of infertilities are due to endometriosis. ultrustructural and histochemical study of endometrium will help to clarify the etiology of endometriosis. objective: the aim of the present study was to investigate the ultrastructure and occurrence of apoptosis in endometrial cells of women with or without endometriosis. materials and methods: in the present case-control stu...

background: female genital tuberculosis is an important cause of secondary amenorrhea and infertility in developing countries where tuberculosis is endemic. objectives: we present three cases in which endometrial tuberculosis was a cause of secondary amenorrhea and infertility.rnpatients and methods: in a retrospective study from january 2007 to june 2010, we conducted 1010 laparoscopies for in...