نتایج جستجو برای: endocrinopathy
تعداد نتایج: 599 فیلتر نتایج به سال:
Despite recent advances in understanding the pathophysiologic mechanisms behind the thalassemia intermedia (TI) phenotype, data on the effects of treatment are deficient. To provide such data, we evaluated 584 TI patients for the associations between patient and disease characteristics, treatment received, and the rate of complications. The most common disease-related complications were osteopo...
OBJECTIVES/HYPOTHESIS To characterize the spectrum, symptoms, progression, and effects of endocrine dysfunction on sinonasal disease in polyostotic fibrous dysplasia (PFD) and McCune-Albright Syndrome (MAS). STUDY DESIGN Retrospective review. METHODS A prospectively followed cohort of subjects with PFD/MAS underwent a comprehensive evaluation that included otolaryngologic and endocrine eval...
POEMS syndrome is a multisystem disorder characterized by polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes. POEMS syndrome is a rare cause of refractory ascites. We report the case of a patient with POEMS syndrome presenting with massive ascites who was treated with very-low-dose lenalidomide and dexamethasone. A 57-year-old Japanese man was admitted to our ...
The POEMS syndrome (coined to refer to polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes) remains poorly understood. Ambiguity exists over the features necessary to establish the diagnosis, treatment efficacy, and prognosis. We identified 99 patients with POEMS syndrome. Minimal criteria were a sensorimotor peripheral neuropathy and evidence of a monoclonal plasmaprolife...
The existing literature on polarization has focused predominantly on spatial polarization and partisanship. This paper extends the focus of polarization to the literature on issue ownership, and competence. Using ANES data from 1972 to 2012, we identify a pattern of partisan polarization in competence assessments in parallel with elite polarization in the US and some evidence of increasing comp...
At the center of debates on deliberative democracy is the issue of how much deliberation citizens experience in their social networks. These “disagreements about disagreement” come in a variety of forms, with scholars advocating different empirical approaches (e.g., Huckfeldt, Johnson, and Sprague 2004; Mutz 2006) and coming to different substantive conclusions. We address these discrepancies b...
Does the religious affiliation of candidates act as a voting cue? Prior research suggests that voters choose which candidate to support under low-information circumstances where the media chooses to report the “horse-race” of politics and candidates choose to maximize votes by keeping their political positions ambiguous (Downs 1957; Page1976). Therefore, voters use candidate characteristics as ...
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