Layer-by-layer (LbL) [1] assembly is a powerful tool for engineering microparticulate structures. On the one hand it allows one to tailor the surface chemistry of microparticles, rendering them responsive to physicochemical stimuli such as pH, ionic strength, light, and so on, to allow bio-specific recognition or just to prevent adsorption of unwanted species [2]. On the other hand, using micro...

Extraordinary water-repelling properties of superhydrophobic surfaces make them novel candidates for a great variety of potential applications. A general approach to achieve superhydrophobicity requires low-energy coating on the surface and roughness on nano- and micrometre scale. However, typical construction of superhydrophobic surfaces with micro-nano structure through top-down fabrication i...

The aim of the present study was to develop novel daptomycin-loaded poly-epsilon-caprolactone (PCL) microparticles with enhanced antibiofilm activity against mature biofilms of clinically relevant bacteria, methicillin-resistant Staphylococcus aureus (MRSA) and polysaccharide intercellular adhesin-positive Staphylococcus epidermidis. Daptomycin was encapsulated into PCL microparticles by a doub...

Nano films consisting of an alternating sequence of positively and negatively charged polyelectrolytes have been prepared by means of the electrostatic layer-by-layer (LBL) sequential assembly technique on treated and untreated mild steel wires. Inhibitor was encapsulated between cationic and anionic polyelectrolyte nano films. This paper mainly focuses on the effect of these nano-films of poly...

Applications of the interface-selective methods of second harmonic (SHG) and sum frequency (SFG) spectroscopy to the investigation of equilibrium and time-dependent properties of interfaces are increasing at an explosive rate.1-53 Among the interfaces studied with these methods are liquid/ gas, solid/gas, and the buried liquid/liquid, liquid/solid, and solid/solid interfaces.35,36,39,41,51,53 I...

Particles capable of homing and adhering to specific vascular biomarkers have potential as fundamental tools in drug delivery for mediation of a wide variety of pathologies, including inflammation, thrombosis, and pulmonary disorders. The presentation of affinity ligands on the surface of a particle provides a means of targeting the particle to sites of therapeutic interest, but a host of other...

The present study involves preparation and evaluation of gastric-mucoadhesive microparticles with Metformin Hydrochloride as model drug for prolongation of gastric residence time. The microparticles were prepared by the emulsification solvent evaporation technique using polymers of Carbomer 934p (C) and Ethylcellulose (EC). The microparticles were prepared by emulsion solvent evaporation method...

The present study involves preparation and evaluation of gastric-mucoadhesive microparticles with Metformin Hydrochloride as model drug for prolongation of gastric residence time. The microparticles were prepared by the emulsification solvent evaporation technique using polymers of Carbomer 934p (C) and Ethylcellulose (EC). The microparticles were prepared by emulsion solvent evaporation method...

We succeeded in fabrication of a free accessible microchannel using an air-liquid interface. To pattern the air-liquid interface in the microfluidic chip, we utilized nano-geometric surface which encloses micropatterned massive nanopillars to enhance the wettability of the surface, which was fabricated by using the hybrid mask lithography technique. Novelties of this paper are shown as follows....