Nerve injury, a significant cause of disability, may be treated more effectively using nerve guidance channels containing longitudinally aligned fibers. Aligned, electrospun nanofibers direct the neurite growth of immortalized neural stem cells, demonstrating potential for directing regenerating neurites. However, no study of neurite guidance on these fibers has yet been performed with primary ...

This paper studies the evolution mechanism of surface rippling in polymer nanofibers under axial stretching. This rippling phenomenon has been detected in as-electrospun polyacrylonitrile in recent single-fiber tension tests, and in electrospun polyimide nanofibers after imidization. We herein propose a one-dimensional nonlinear elastic model that takes into account the combined effect of surfa...

Articles you may be interested in Large effect of titanium precursor on surface reactivity and mechanical strength of electrospun nanofibers coated with TiO2 by atomic layer deposition Light-induced electron paramagnetic resonance evidence of charge transfer in electrospun fibers containing conjugated polymer/fullerene and conjugated polymer/fullerene/carbon nanotube blends Appl. Microwave Hall...

Electrospinning is a versatile technique to prepare polymer fibers in nano to micrometer size ranges using very high electrostatic fields. Electrospun nanofibers with tunable porosity and high specific surface area have various applications, including chromatographic supports for protein separation, biomedical devices, tissue engineering and drug delivery matrices, and as key components in sola...

Electrospinning of collagen and chitosan blend solutions in a 1,1,1,3,3,3-hexafluoroisopropanol/trifluoroacetic acid (v/v, 90/10) mixture was investigated for the fabrication of a biocompatible and biomimetic nanostructure scaffold in tissue engineering. The morphology of the electrospun collagen-chitosan nanofibers was observed by scanning electron microscopy (SEM) and stabilized by glutaralde...

One major method used to evaluate the biocompatibility of porous tissue engineering scaffolding materials is MTT (3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay. The MTT cell viability assay is based on the absorbance of the dissolved MTT formazan crystals formed in living cells, which is proportional to the number of viable cells. Due to the strong dye sorption capability ...

Pioneer works on nanocomposites were focused in carbon nanofibers or nanotubes dispersed in epoxy matrix, a viscous liquid facilitating the compounding stage. The interest in developing new composites aimed for biomedical applications led us to design new nanocomposites based in biodegradable polymers with demonstrated biological performance. We report herein the development of micro-nano compo...

Electrospinning is a rapidly growing polymer processing technology as it provides a viable and simple method to create ultra-fine continuous fibers. This paper presents an in-depth review of the mechanical properties of electrospun fibers and particularly focuses on methodologies to generate high strength and high modulus nanofibers. As such, it aims to provide some guidance to future research ...

Flexible, magnetic, and hierarchical porous NiFe2O4@SiO2 nanofibrous membranes were prepared by combining the gelatin method with electrospun nanofibers. The membranes exhibited prominent mechanical strength and mesoporosity, as well as multifunctionality of magnetic responsiveness, dye adsorption, and emulsion separation.

Wound dressing applications of nanofibers is a progressive filed of research which could be enhanced by using medicinal plant extract to bring some more advantages. Here we optimized the electrospinning method for fabrication of polycaprolactone-gelatin mixed with a medicinal plant extract, calendula offlcinalis. Characterization techniques including Fourier-transform infrared spectroscopy (FTI...