Abstract Electrochemotherapy has emerged as a valuable tool in the treatment of cutaneous malignancies that are unamenable to surgical resection. Despite growing recognition and recommendation national guidelines, date, no Level 1 evidence exists comparing its use radiotherapy management malignancies. A systematic review meta-analysis will be undertaken line with Cochrane Handbook Preferred Rep...

BACKGROUND Advanced carcinoma of the head represents a substantial health problem in cats for local control and overall survival. OBJECTIVES Evaluate the capability of electrochemotherapy (ECT) to improve bleomycin efficacy in cats with periocular carcinoma and advanced carcinoma of the head. ANIMALS Twenty-one cats with periocular carcinoma (17 squamous cell carcinoma [SCC] and 4 anaplasti...

PURPOSE OF REVIEW This article describes why this review is timely and relevant. To report on the recent research, which advances our understanding and practice of palliative wound care (wound-related pain and symptom management or wound palliation). RECENT FINDINGS This article describes the main themes in the literature covered by the article. The main themes include the problem of malodour...

BACKGROUND The in vitro cytotoxic activity of two new platinum(II) complexes (3P-SK and PtAMP) in comparison with cisplatin (CDDP), oxaliplatin (OXA) and carboplatin (CARBO) was determined in four different human tumour cell lines. The in vivo efficiencies of CDDP and 3P-SK in MCA mammary carcinoma tumours induced in CBA mice were compared. MATERIALS AND METHODS The in vitro cytotoxicity of t...

Cell permeabilization by electric pulses (EP), or electroporation, is widely used for intracellular delivery of drugs and plasmids, as well as for tumour and tissue ablation. We found that cells pre-treated with 100-μs EP develop delayed hypersensitivity to subsequent EP applications. Sensitizing B16 and CHO cells by splitting a single train of eight 100-μs EP into two trains of four EP each (w...