BACKGROUND Eosinophil cationic protein (ECP) and eosinophil derived-neurotoxin (EDN) are homologous ribonuclease (RNAse) A family proteins. The objective of the present study was to in silico characterize ECP and EDN with respect to their cytotoxic activities. MATERIALS AND METHODS Structural, physicochemical, and conserved domain characterizations were carried-out using open-source software,...

The method proposed by the author is intended for assistance in decision-making (concerning changes of connections) by operators of complex distribution systems during states of malfunction (particularly in the events of malfunctions, for which the consequences encompass extended parts of the network), through designation of connection action scenarios (creating substitute configurations). It i...

Gaussian processes (GPs) are widely used in surrogate-assisted evolutionary optimization of expensive problems mainly due to the ability provide a confidence level their outputs, making it possible adopt principled surrogate management methods, such as acquisition function Bayesian optimization. Unfortunately, GPs become less practical for high-dimensional multiobjective and many-objective comp...

BACKGROUND AND OBJECTIVES Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by loss of motor neurons in the brainstem, motor cortex, and spinal cord. Oxidative stress and neuroinflammation have been implicated in the pathophysiology of ALS. Members of the family of damage-associated molecular patterns, including reactive oxygen species, high-mobility g...

Transmission network expansion planning (TNEP) is an important component of power system planning. Itdetermines the characteristics and performance of the future electric power network and influences the powersystem operation directly. Different methods have been proposed for the solution of the static transmissionnetwork expansion planning (STNEP) problem till now. But in all of them, STNEP pr...

This paper proposes a methodology for practical siting and sizing of Hybrid energy systems (HESs) consist of: wind turbine (WT), photovoltaic (PV) and combined heat and power (CHP) units. In this method, the interaction of Plug-in Electric Vehicles (PIEVs) in the electric distribution system is considered. Electric Vehicle are seen to have some negative impacts on electric distribution system p...