The effects of saturated and unsaturated fatty acids on the growth of Bordetella pertussis strain 114 in defined medium were tested. Individual fatty acids were found to be either inhibitory or stimulatory to growth, depending on concentration. Myristic (C14), pentadecanoic (C15), and palmitic (C16) acids were the most inhibitory saturated fatty acids tested. B. pertussis 114 was extremely sens...

Comparative studies were made of the uptake and metabolism of cis- and trans-octadecenoic acids by the perfused chicken liver. No differences were observed in the rates of uptake of the isomers. There was considerable incorporation of radioactivity into triglycerides and phospholipids, and some release of labelled lipid into the perfusate was observed. The cis-fatty acids were more readily inco...

The species Hancornia speciosa (mangabeira) has varied potential. bark astringent properties, latex is used for tuberculosis, ulcers, herpes, dermatoses and warts, leaf tea menstrual cramps the root decoction to treat dislocations hypertension. aim of this work was analyze chemical composition fixed oil antibacterial activities alone or in association with aminoglycosides against standard MDR b...

To investigate the effects of a dam's dietary elaidic acid (EA) intake during pregnancy and lactation on the fatty acid composition of plasma, erythrocyte membrane, and brain in rat pups, we fed two groups of dams either a soybean oil diet (SOD) or a shortening diet (SHD) containing soybean oil (10%) or shortening (10%), respectively. Although EA was not detected in the SOD, EA accounted for 25...

BACKGROUND Mono-unsaturated fatty acids (MUFAs) like oleic acid have been shown to cause apoptosis of cultured endothelial cells by activating protein phosphatase type 2C alpha and beta (PP2C). The question arises whether damage of endothelial or other cells could be observed in intact animals fed with a trioleate-enriched diet. METHODOLOGY/PRINCIPAL FINDINGS Dunkin-Hartley guinea pigs were f...

Trans fatty acids are found mainly in processed foods. It has been shown that when their intake is high, total cholesterol, LDL-cholesterol and triacylglycerols are elevated, while HDL-cholesterol decreases. To evaluate a possible effect of these compounds, even in low amounts, C57Bl/6J mice were fed for 7 weeks a diet containing 13.6 % energy as partially hydrogenated rapeseed oil-enriched die...