OBJECTIVE The association between restless legs syndrome (RLS), cardiovascular diseases (CVD) and hypertension is inconsistent. This case-control study examined i) the association between primary RLS, CVD and hypertension by taking into account many potential confounders and ii) the influence of RLS duration, severity and treatment, sleep and depressive symptoms on CVD and hypertension in prima...

OBJECTIVES Venous disease was proposed as a cause of restless legs syndrome (RLS) by Dr Karl A Ekbom in 1944, but has since remained largely unexplored. This study examines the effect of endovenous laser ablation (ELA) in patients with concurrent RLS and duplex-proven superficial venous insufficiency (SVI). METHODS Thirty-five patients with moderate to very severe RLS (as defined by the 2003 ...

Insomnia and excessive sleepiness are among the most commonly reported sleep problems related to shift work. Sleep-related movement disorders have, however, received far less attention in relation to such work schedules. The objective of this study was to investigate the association between different shift work schedules and the prevalence of Restless legs syndrome/Willis-Ekbom disease (RLS/WED...

Objective A single-blind randomised controlled trial was conducted to test the efficacy of Longden’s counterstrain technique for restless legs syndrome (RLS) and the feasibility of the trial methodology. Methods Participants were adults with moderate to severe and persistent RLS, randomized to receive either active or control intervention. The control intervention (B) involved Counterstrain man...