Females of many animal species seek mating opportunities with multiple males, despite being able to obtain sufficient sperm to father their offspring from a single male. In animals that live in stable social groups, females often choose to mate outside their group resulting in extra-group paternity (EGP). One reason proposed to explain female choice for extra-group males is to obtain compatible...

PURPOSE The leaves of Gynura procumbens (Lour.) Merr. has been traditionally used as anticancer. Ethanolic extract of G. procumbens leaves (EGP) showed cytotoxic activity and anticancer activity in animal cancer model. This study was conducted to observe antiproliferative effect using male rat's liver cells induced by 7,12-dimethylbenz(a)antracene (DMBA). METHODS Forty days old Sprague Dawley...

In statistics, samples are drawn from a population in data-generating process (DGP). Standard errors measure the uncertainty sample estimates of parameters. science, evidence is generated to test hypotheses an evidence-generating (EGP). We claim that EGP variation across researchers adds uncertainty: non-standard errors. To study them, we let 164 teams six on same sample. find sizeable, par wit...

Let A be an idempotent algebra on a finite domain. We combine results of Chen [6] and Zhuk [10] to argue that if Inv(A) satisfies the polynomially generated powers property (PGP), then QCSP(Inv(A)) is in NP. We then use the result of Zhuk to prove a converse, that if Inv(A) satisfies the exponentially generated powers property (EGP), then QCSP(Inv(A)) is co-NP-hard. Since Zhuk proved that only ...

OBJECTIVE To assess glucose-lowering mechanisms of sitagliptin (S), metformin (M), and the two combined (M+S). RESEARCH DESIGN AND METHODS We randomized 16 patients with type 2 diabetes mellitus (T2DM) to four 6-week treatments with placebo (P), M, S, and M+S. After each period, subjects received a 6-h meal tolerance test (MTT) with [(14)C]glucose to calculate glucose kinetics. Fasting plasma...

To determine the effect of insulin-like growth factor I (IGF-I) on glucose metabolism in cirrhosis, a 2-h euglycemic clamp with IGF-I (0.65 nmol ⋅ kg-1 ⋅ min-1) or insulin (12 pmol ⋅ kg-1 ⋅ min-1) was performed in awake rats with carbon tetrachloride-induced liver cirrhosis. Rates of [3-3H]glucose-determined whole body glucose turnover were similar in the fasting state in cirrhotic and control ...

The hyperglycemic effects of epinephrine (Epi) are established; however, the modulation of Epi-stimulated endogenous glucose production (EGP) by glucose and insulin in vivo in humans is less clear. Our aim was to determine the effect of exogenously increased plasma Epi concentrations on insulin and glucose dynamics. In six normal control subjects, we used the labeled intravenous glucose toleran...

In this work, a novel insulin-glucagon-glucose model is proposed, where the glucagon effect on endogenous glucose production (EGP) described by dynamics of receptors. order to assess quality model, its parameters are fitted in such way that influence EGP isolated. Experimental data used validate structure and show receptor allow explain some glucagon-related phenomena observed clinical data. Th...