Cidofovir [(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine, HPMPC] is an acyclic nucleoside analog approved since 1996 for clinical use in the treatment of cytomegalovirus (CMV) retinitis in AIDS patients. Cidofovir (CDV) has broad-spectrum activity against DNA viruses, including herpes-, adeno-, polyoma-, papilloma- and poxviruses. Among poxviruses, cidofovir has shown in vitro activity ag...

Molluscum contagiosum is a common viral skin infection in children with atopic diathesis and not rare in HIV patients. We report a 45-year-old psoriasis patient who developed eruptive mollusca contagiosa during an antipsoriatic treatment with efalizumab.

A 7-year-old girl presented with solitary, asymptomatic, nodule near right angle of mouth for 8 months. The lesion started as a small papule and increased in size over time. The child was otherwise healthy. On examination, single erythematous nodule measuring 1 cm, and of soft to firm consistency, was seen near the right angle of mouth. The top of the lesion was eroded and covered with crust. R...

AIM The objective of this study was to screen the prevalence of contagious ecthyma (CE) among the goat population of Assam owing to its high prevalence rate. MATERIALS AND METHODS In this study, a total of 231 serum samples were collected from 12 districts of Assam during September 2013 to July 2014. The serum samples were tested for the presence of antibodies against Orf virus (ORFV) by indi...

Orf virus is a parapoxvirus that causes recurring contagious ecthyma or orf disease in goat, sheep and other wild and domestic ruminants. Infected animals show signs of pustular lesions on the mouth and muzzle and develop scabs over the lesions. Although the infection is usually cleared within 1-2 months, delayed growth and associated secondary infections could still impact the herds. Orf virus...

Received May 18, 2010, Revised June 10, 2010, Accepted for publication June 10, 2010 Corresponding author: Eun-So Lee, M.D., Department of Dermatology, Ajou University School of Medicine, San 5 Wonchon-dong, Yeongtong-gu, Suwon 443-721, Korea. Tel: 82-31-219-5190, Fax: 82-31219-5189, E-mail: [email protected] Fig. 1. Hyperkeratotic projection on the umbilicated papule in the posterior auricular ar...