Major depressive disorder (MDD) and Parkinson's disease (PD) share symptoms such as tremor. Bupropion, a norepinephrine-dopamine reuptake inhibitor, shows weak dopamine transporter (DAT) occupancy. We report here on a patient with MDD whose hand tremors might have been misdiagnosed as PD by single-photon emission computed tomography (SPECT) under bupropion use. A 66-year-old male patient with M...

Parkinson’s disease is a progressive degenerative neurological disorder which mainly affects the motor system of body and it characterized by resting tremors, slowness movements, rigidity, gait disturbances/postural instability. It correlated with Kampa Vata [Disease associated tremors in body] Ayurveda, [Indian ancient science for healthy life] as Sarvanga / Shiro [tremors all over or head]. V...

Although debate exists as to the incidence and prevalence of antipsychotic-induced tardive dyskinesia (TD), it is readily accepted that antipsychotics can and often do induce this potentially irreversible movement disorder. Studies commonly report a prevalence rates of 25 to 40 percent and incidence rates of 1 to 3 percent annually.'-' Contemporary and controversial research suggests that tardi...

1. Singular vs. general causation In many people, caffeine causes slight muscle tremors, particularly in their hands. In general, the Caffeine → Muscle Tremors causal connection is a noisy one: someone can drink coffee and experience no hand shaking, and there are many other factors that can lead to muscle tremors. Now suppose that Jane drinks several cups of coffee and then notices that her ha...

The increase in life expectancy, according to the World Health Organization, is a fact, and with it rises incidence of age-related neurodegenerative diseases. most recurrent symptoms are those associated tremors resulting from Parkinson’s disease (PD) or essential (ETs). main alternatives for treatment these patients medication surgical intervention, which sometimes have restrictions side effec...

BACKGROUND Delayed seizures have been reported with overdoses of bupropion extended-release (XL). This study systematically evaluates the frequency and timing of seizures and an association between other toxic effects (ie, agitation, tremors, and hallucinations) and seizures. METHODS A 3-year multi-poison center observational study of hospitalized patients with ingestion of bupropion XL >or=6...

Medication is the predominant method for the management of patients with movement disorders. However, there is a fraction of patients who experience limited relief from pharmaceuticals or experience bothersome side-effects of the drugs. Deep brain stimulation (DBS) and surgical lesioning of the thalamus and basal ganglia are respected neurosurgical procedures, with valued success rates and a ve...

Patients who suffer from tremors are initially treated with pharmecuticals. Although medication has proven to be effective in achieving tremor control for some patients, there is still a fraction of patients who seek neurosurgical alternatives due to unacceptable tremor relief or side-effects from the prescribed drugs. Invasive neurosurgical procedures include radiofrequency thalamotomy and in ...

Intraperitoneal injection of ethanol (1-2 g/kg) and chlordiazepoxide (2-16 mg/kg) suppressed susceptibility to audiogenically induced, clonic-tonic seizures and antagonized forelimb tremor in rats undergoing ethanol withdrawal, 30 min after treatment. However, a smaller dose of ethanol (0.5 g/kg) actually increased clonic seizure frequency, suggesting that ethanol exerts a biphasic proconvulsan...