OBJECTIVE To evaluate a fully automated system for liquid-based cytology (LBC): the NovaPrep® Processor System (NPS), which is based on the new concept of double decantation, versus conventional cytology (CC), the gold standard for cytology. STUDY DESIGN We performed a preliminary comparative study involving 1,129 female patients who underwent sampling for a Pap test; the sample was first sme...

BACKGROUND The incidence of cervical cancer in South Africa (SA) remains high, and the current screening programme has had limited success. New approaches to prevention and screening tactics are needed. OBJECTIVES To investigate acceptance of school-based human papillomavirus (HPV) vaccination, as well as the information provided, methods of obtaining consent and assent, and completion rates ...

PURPOSE To assess knowledge, attitudes and cervical cancer screening behavior of Bangkok Metropolitan women. MATERIALS AND METHODS Thai women, aged 25-to-65 years old, having lived in Bangkok for 5 years or more were invited to participate in the study. After signing informed consent, all women were asked to complete a self-questionnaire (Thai language) with literate assistance if needed. The...

INTRODUCTION We have previously developed a portable Pocket Colposcope for cervical cancer screening in resource-limited settings. In this manuscript we report two different strategies (cross-polarization and an integrated reflector) to improve image contrast levels achieved with the Pocket Colposcope and evaluate the merits of each strategy compared to a standard-of-care digital colposcope. Th...

conclusions both task-related and resting fmri techniques have the potential to detect early brain dysfunction related to ad. however, the use of fmri in ad populations thus far has been limited to a relatively small number of research groups. results bold fmri is considered to reflect the joined synaptic activity of neurons through mri signal changes because of alterations in blood flow, blood...

breast cancer is characterized by a distinct metastatic pattern involving the regional lymph nodes, bone marrow, lung and liver. tumour cell migration and metastasis share many similarities with leukocyte trafficking, which is critically regulated by chemokines and their receptors. detection of breast cancer and its metastasis at the earliest stage is important for the management and prediction...

The focus of this study was to determine if early detection of mutant p53 accumulation may be an early indicator of tumor aggressiveness and transformation to invasive breast cancer. For this purpose, the p53 content of 100 human breast biopsies classified as ductal carcinoma (DCIS), was evaluated by immunohistochemical method. All specimens were microscopically classified into histologic types...

breast cancer within incident of one million new cases each year has become one of the most common malignancies and leading cause of death among females. this disease is comprised of about 18% of women cancers. the availability of early detection and improved treatments may decrease the mortality rates which reflected in the united states and many other western countries. breast cancer in over ...