BACKGROUND Acute cartilage injuries induce cell death and are associated with an increased incidence of osteoarthritis development later in life. The objective of this study was to investigate the effect of posttraumatic cyclic compressive loading on chondrocyte viability and apoptosis in porcine articular cartilage plugs. HYPOTHESIS Compressive loading of acutely injured cartilage can mainta...

The loading margin to a saddle-node or fold bifurcation measures the proximity to voltage collapse blackouts of electric power transmission systems. Sensitivities of the loading margin can be used to select controls to avoid voltage collapse. We analytically justify the use of static models to compute loading margins and their sensitivities and explain how the results apply to underlying dynami...

Mesenchymal stem cells (MSCs) are an attractive cell source for cartilage tissue engineering given their ability to undergo chondrogenesis in 3D culture systems. Mechanical forces play an important role in regulating both cartilage development and MSC chondrogenic gene expression, however, mechanical stimulation has yet to enhance the mechanical properties of engineered constructs. In this stud...

In the present article a numerical procedure is developed for dynamic analysis of single and double autofrettage of thick–walled FG cylinders under transient loading. The governing differential equations are discretized and presented in explicit Lagrangian formalism. The explicit transient solution of discrete equations are obtained on the meshed region and results for stress and strain distrib...

Large strains in semiconductors are expected to be more common in future electronic devices utilizing nanostructure components. Hydrostatic pressure (HP) and uniaxial stress (US) loading have inherent limitations for probing the desired strain conditions. Uniaxial strain loading, achieved in dynamic compression experiments, is particularly attractive for attaining well-defined, large strains an...

During consolidation process of saturated cohesive soil the soil stiffness increases. Increase of the effective stress due to dissipation of excess pore pressure causes additional stiffness of soil mass. This phenomenon has a very important effect on the behavior of saturated cohesive soils during dynamic loading. In the current investigation the changes in maximum shear modulus. Gmax and dampi...

Stochastic amorphous Pd43Ni10Cu27P20 foams were tested in quasistatic and dynamic loading. The strength/porosity relations show distinct slopes for the two loading conditions, suggesting a strain-rate-induced change in the foam yielding mechanism. The strength/porosity correlation of the dynamic test data along with microscopy assessments support that dynamic foam yielding is dominated by plast...

Nowadays, due to the necessity of increasing quality awareness in the food sector and its health, the non-destructive computed tomography (CT) method, which is one of the most widely used methods because of the ability to detect internal bruise in a non-destructive way, attracted so much attention. By using the non-destructive CT method a total of 81 healthy pears was selected and then subjecte...

While the dynamic linking mechanism of modern programming languages, such as Java, allows loading of classes dynamically, it does not allow class reloading. Hence, dynamic linking facilitates development of component platforms, such as eclipse RCP, which supports dynamic loading but not dynamic updates of components, since this requires reloading. This paper presents an approach that enhances e...