Aim: MicroRNA-126 (miR-126) exerts beneficial effects on vascular integrity, angiogenesis, and atherosclerotic plaque stability. The purpose of this investigation was to analyze the dose-response relationship of high-intensity interval training (HIIT) on miR-126-3p and -5p levels. Methods: Sixty-one moderately trained individuals (females = 31 [50.8%]; 22.0 ± 1.84 years) were consecutively recr...

There is growing consensus that exercise improves cognitive functioning, but research is needed to identify exercise interventions that optimize effects on cognition. The objective of this pilot study was to evaluate Taekwondo implemented in public middle school physical education (PE). Two classes were randomly assigned to either: five sessions per week of PE or three sessions of PE and two se...

The purpose of this exercise session is to give an overview of several aspects of scientific computing. First, we focus on the solving of an elliptic boundary value problem with the Finite Element Method. In a first part, we focus on the implementation of a very basic PDE model, hoping this may get the reader to be familiar with the software FreeFem++, which makes it very easy to handle finite ...

BACKGROUND Exercise is beneficial for breast cancer patients during chemotherapy but adherence to different types and doses of exercise is a challenge. The purpose of this study was to examine predictors of adherence to different types and doses of exercise during breast cancer chemotherapy in a multicenter randomized controlled trial. METHODS Breast cancer patients in Edmonton, Vancouver, an...

The aim of the present study was to examine the influence of intermittent hypoxia at rest and in combination with long-term high-intensity swimming exercise on lipid peroxidation and antioxidant defense system adaptation in skeletal muscles differing in fiber type composition. High-intensity chronic exercise was performed as swimming training with load that corresponded to ~ 75 % VO2max (30 min...

BACKGROUND Gastrointestinal (GI) disturbances are often reported by long distance runners and are more common in women, particularly after prolonged high intensity exercise. OBJECTIVES To determine whether these symptoms could be associated with alterations in GI motility. METHODS Small bowel and colonic transit were measured using pH telemetry in a group of 11 female athletes (age 22 to 53...

BACKGROUND Astronauts may have difficulty adhering to exercise regimens at vigorous intensity levels during long space missions. Vigorous exercise is important for aerobic and musculoskeletal health during space missions and afterwards. A key impediment to maintaining vigorous exercise is motivation. Finding ways to motivate astronauts to exercise at levels necessary to mitigate reductions in m...

BACKGROUND The effect of exercise protocol on the slope of the relationship between minute ventilation and carbon dioxide production (deltaVE/deltaVCO2) has not fully been studied. METHODS Twenty-five healthy volunteers performed two sessions of incremental bicycle exercise, one with a rapidly increasing staged (RIS: 25W every minute) protocol and another with a slowly increasing staged (SIS:...