xercise or pharmacological stress myocardial perfusion single-photon emission computed tomography (SPECT) has been used in daily clinical practice as a reliable diagnostic modality and a prognostic marker for patients with coronary artery disease.1–3 We herein report atypical exercise stress myocardial perfusion SPECT imaging in a patient with effort angina pectoris. A 58-year-old male who had ...

Twenty-five patients with a clinically suggestive diagnosis of pulmonary embolism were referred directly from the accident and emergency department for a ventilation and perfusion isotope scan. On the basis of a negative scan, the authors were able to discharge 19 patients. The advantages of having direct access to isotope imaging are described.

UNLABELLED High kidney radiation doses during clinical peptide receptor radionuclide therapy (PRRT) with β-particle-emitting radiolabeled somatostatin analogs will lead to renal failure several months after treatment, urging the coinfusion of the cationic amino acids lysine and arginine to reduce the renal radiation dose. In rat PRRT studies, renal protection by the coadministration of lysine w...

Measurement of energy expenditure in humans is required to assess metabolic needs, fuel utilisation, and the relative thermic effect of different food, drink, drug and emotional components. Indirect and direct calorimetric and non-calorimetric methods for measuring energy expenditure are reviewed, and their relative value for measurement in the laboratory and field settings is assessed. Where h...

Quantitative SPECT as well as simultaneous acquisition of multiple isotopes with SPECT in the clinical field, although clinically interesting, are still limited by reconstruction artifacts and computing power. As a considerable step in this direction, we have implemented an efficient reconstructor with variance reduced Monte-Carlo-simulation in the forward and/or backward projection of an OS-EM...

Working with ytterbium ~Yb!, we demonstrate dual-isotope magneto-optic traps of extreme experimental simplicity yet containing either fermion-boson or boson-boson isotope pairs. Pairs studied include Yb1Yb ~a fermion-boson mixture! and Yb1Yb and Yb1Yb ~boson-boson mixtures!. Trapping is performed using the Yb (6s)S0-(6s6p) P1 transition, an uncooled thermal source, and bichromatic trapping beam...

Lipophilic cationic technetium-99m-complexes are widely used for myocardial perfusion imaging (MPI). However, inherent uncertainties in the supply chain of molybdenum-99, the parent isotope required for manufacturing 99Mo/99mTc generators, intensifies the need for discovery of novel MPI agents incorporating alternative radionuclides. Recently, germanium/gallium (Ge/Ga) generators capable of pro...