OBJECTIVES Recognizing the importance of patient-reported outcomes, this longitudinal, prospective study examined: Changes in health-related quality of life (HRQOL) over seven months following antiepileptic drug (AED) initiation and the relationship of seizures, AED side-effects, and AED type to HRQOL. METHOD Parents of 124 children with newly diagnosed epilepsy completed measures of HRQOL an...

Metabolic syndrome (MetS) is a clustering of several cardiovascular risk factors that include: obesity, dyslipidemia, hypertension and high blood glucose, and often requires multidrug pharmacological interventions. The management of MetS therefore requires high healthcare cost, and can result in poor drug treatment compliance. Hence drug therapies that have pleiotropic beneficial effects may be...

Learning outcomes On completion of this article you should have: • an understanding of the factors that predispose the elderly to adverse drug reactions • a detailed knowledge of ocular side effects of systemic drugs commonly prescribed to the elderly • a detailed knowledge of the side effects of topical ophthalmic drugs commonly used by elderly patients • an understanding of the importance of ...

depression is a serious disorder in today’s society, with the estimates of lifetime prevalence being as high as 21% of the general population in some developed countries. as defined by the american psychiatric association, depression is a heterogeneous disorder often manifested with symptoms at the psychological, behavioral, and physiological levels. such patients are often reluctant to take sy...

a 73-year-old female patient developed a generalized tonic-clonic seizure on the 6th day after treatment with moxifloxacin 400 mg daily intravenously for appendicitis. this patient had atrial fibrillation and history of a surgery for intracerebral hemorrhage, with impaired renal function and liver function, but without history of seizures. moxifloxacin was discontinued and switched to cefuroxim...

background: the challenge of antiepileptic drugs (aeds) management is to attain the best compromise between the desire to maximize seizure control and the need to keep side‑effects within tolerable limits for the individual patient. to reduce devastation in iranian epileptic patients, the aim of this study was to explore the overall outcome following aeds prescription. methods: a cross‑sectiona...

how to cite this article: karimzadeh p, bakrani v. antiepileptic drug-related adverse reactions and factors influencing these reactions. iran j child neurol. 2013 summer; 7(3):23-27.   objective according to the basic role of drug side effects in selection of an appropriate drug, patient compliance and the quality of life in epileptic patients, and forasmuch as new dugs with unknown side effect...