Liver disorder may cause liver inflammation or tissue injury and affects liver physiologic condition. Natural products that are found in the form of vegetables, fruits, plant extract, herbs, and animals, have been traditionally and clinically used for treating liver disorders. They are specific chemical compounds that usually have biological activities for use in drug evaluation and design. Man...

The medicinal use of natural products—compounds that are derived from natural sources such as plants, animals or micro-organisms—precedes recorded human history probably by thousands of years. Palaeoanthropological studies at the cave site of Shanidar, located in the Zagros Mountains of Kurdistan in Iraq, have suggested that more than 60,000 years ago, Neanderthals might have been aware of the ...

This review covers some of the opportunities which currently exist to exploit plants for their natural products as templates for new antibacterial substances. This is a timely exercise given the continuing and developing problems of bacterial resistance, and in particular multidrug-resistance (MDR). Some of the challenges which are evident with bacterial resistance will be described and the str...

Liver disease is any condition that may cause liver inflammation or tissue damage and affects liver function. Natural products that are found in vegetables, fruits, plant extracts, herbs, insects, and animals, have been traditionally used for treating liver diseases. They are chemical compounds that usually have biological activities for use in drug discovery and design. Many natural products h...

The bark of the Mimosa tenuiflora (Willd.) Poiret (Leguminoseae) tree, known as tepescohuite in Mexico, is commonly used in this country and in Central America to elaborate different products for the treatment of skin burns and lesions. The cicatrizing properties of extracts obtained from this bark have been scientifically studied, attributing the main biological activity to its tannin and sapo...

The combination of plant cell culture methodology with synthetic chemistry affords an attractive route to the synthesis of complex natural products and related compounds of industrial importance. Plant cell cultures which often provide "unique" enzyme systems can be employed effectively as "reagents" in the biotransformation of synthetic substrates to desired end products. Such conversions are ...

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Natural products have been the single most productive source of leads for the development of drugs. Over a 100 new products are in clinical development, particularly as anti-cancer agents and anti-infectives. Application of molecular biological techniques is increasing the availability of novel compounds that can be conveniently produced in bacteria or yeasts, and combinatorial chemistry approa...

For the past few decades, there has been a considerable in research interest in the area of natural product delivery using particulate for controlling plant pathology. The secondary metabolites in plants have been used in the formulation of nanoparticles through increase the effectiveness of therapeutic compounds used to reduce the spread of plant diseases, while minimizing side effects for bei...

Advances in analytical methods and bioassay development have helped to push forward the research in natural products. In plant extracts and nutraceuticals, bioactive compounds are part of a complex mixture. The development of high-resolution methods related to HPLC for both chemical and biological profiling has significantly increased the efficiency of classical bioactivity-guided fractionation...