Background and Aim: Preparation of tooth structure by laser systems produces a surface with different characteristics. Therefore, selecting an appropriate bonding system is necessary to achieve the maximum bond strength. The aim of this study was to compare the bond strength of Adper Single Bond 2 adhesive and Single Bond Univer-sal to dentin prepared by bur or laser. Materials and Methods: ...

Mucoadhesive controlled-release devices can improve the effectiveness of a drug by maintaining the drug concentration between the effective and toxic levels, inhibiting the dilution of the drug in the body fluids, and allowing targeting and localization of a drug at a specific site. Acrylic-based hydrogels have been used extensively as mucoadhesive systems. They are well suited for bioadhesion ...

Poor drug distribution and short drug half-life within tumors strongly limit efficacy of chemotherapies in most cancers, including primary brain tumors. Local or targeted drug delivery via controlled-release polymers is a promising strategy to treat infiltrative brain tumors, which cannot be completely removed surgically. However, drug penetration is limited with conventional local therapies si...

background: the aim of this study was to determine the microtensile bond strength (μtbs) of ceramic and composite computer aided design‑computer aided manufacturing (cad‑cam) blocks bonded to dentin using different adhesive strategies. materials and methods: in this in vitro study, 30 crowns of sound freshly extracted human molars were sectioned horizontally 3 mm above the cementoenamel junctio...

Background and Aim: Data regarding the efficacy of universal adhesives are limited. This study aimed to assess the durability of a universal adhesive bond to superficial dentin using etch and rinse and self-etch modes. Materials and Methods: In this in vitro, experimental study, 32 sound molars were randomly divided into two groups of Scotchbond Universal adhesive with two-step etch and rins...

We measured the pH, water-vapor permeability, adhesive force, peeling-force, elongation rate, support flexibility, and peeling time of medicinal and over-the-counter (OTC) tape preparations containing felbinac. When measuring the pH of each preparation, Felnabion (pH 4.5) was weakly acidic, and EMEC and Tokuon (pH 7.0) were neutral. When measuring the water-vapor permeability of each preparatio...

An improved interfacial drug delivery system (DDS) based on polyelectrolyte complex (PEC) coatings with controlled drug loading and improved release performance was elaborated. The cationic homopolypeptide poly(l-lysine) (PLL) was complexed with a mixture of two cellulose sulfates (CS) of low and high degree of substitution, so that the CS and PLL solution have around equal molar charged units....

statement of the problem: monomer viscosity and solvent evaporation can be affected by the adhesive system temperature. higher temperature can elevate the vapor pressure in solution and penetration of adhesive in smear layer. bonding mechanism may be influenced by the adhesive temperature. purpose: this study aimed to evaluate the effect of pre-heating on shear bond strength of etch-and-rinse a...