Background: ACDRs (Adverse cutaneous Drug Reactions) is a major problem in drug therapy and is one of the leading causes of morbidity and mortality in health care. Aims & Objective: To study the clinical pattern, most common offending drugs & relation between absolute eosinophil count & various ACDRs. Materials and Methods: The prospective observational study was carried out from April 2010 to ...

Drug eruptions are among the most common cutaneous disorders encountered by dermatologists. They occur in many forms and mimic many dermatoses. Fixed Drug Eruption (FDE) has its own characteristics and may be associated with ingestion of a number of agents. The incidence of FDE induced by a specific drug depends on the frequency with which the agent is used in a given part of the world. Recentl...

3. Thirion L, Nikkels AF, Piérard GE. Etoricoxib-induced erythemamultiforme-like eruption. Dermatology. 2008;216:227--8. 4. Kreft B, Wohlrab J, Bramsiepe I, Eismann R, Winkler M, Marsch WC. Etoricoxib-induced toxic epidermal necrolysis: successful treatment with infliximab. J Dermatol. 2010;37:904--6. 5. Augustine M, Sharma P, Stephen J, Jayaseelan E. Fixed drug eruption and generalised erythem...

Pegylated or non-pegylated α-interferon are frequently used medications for the treatment of both chronic hepatitis B and chronic hepatitis C. Skin disorders, which are mainly comprised of eczematous dermatitis, are frequently seen during treatment with this drug. However, drug eruption or morbilliform eruptions due to interferons have been rarely reported so far. We herein describe a patient w...

3. Thirion L, Nikkels AF, Piérard GE. Etoricoxib-induced erythemamultiforme-like eruption. Dermatology. 2008;216:227--8. 4. Kreft B, Wohlrab J, Bramsiepe I, Eismann R, Winkler M, Marsch WC. Etoricoxib-induced toxic epidermal necrolysis: successful treatment with infliximab. J Dermatol. 2010;37:904--6. 5. Augustine M, Sharma P, Stephen J, Jayaseelan E. Fixed drug eruption and generalised erythem...

macular or maculopapular skin reactions are frequent events in skin allergies as well as in viral infections. clinically, the differentiation may be difficult in the absence of a clear relationship with drug intake or in the failure to detect measles virus-specific antibodies. studies on drug-specific t cell lines and t cell clones isolated from skin-allergy patients have suggested that these c...

Two volcanic eruptions in the Sumatra-Andaman arc that followed the disastrous M 9.3 earthquake of 26 December 2004 raise the question of whether these eruptions were triggered by the earthquake. Here we present new evidence to suggest that earthquake-induced decompression of the volcano magma systems leads to such eruptions. Numerical modeling reveals that other megathrust earthquakes induced ...