CONTEXT In ecological momentary assessment (EMA), participants electronically report their activities and moods in their daily environments in real time, enabling a truly prospective approach to the study of acute precipitants of behavioral events. Ecological momentary assessment has greatly enhanced the study of tobacco addiction, but its use has rarely been attempted in individuals with cocai...

Eluxadoline is a novel drug approved for the management of diarrhea predominant irritable bowel syndrome (IBS-D). It has unique pharmacology and works on three different opioid receptors. Several Phase II and III clinical trials have demonstrated eluxadoline's efficacy in reducing symptoms related to IBS-D. Clinical trial results and postmarketing reports show a risk of pancreatitis in patients...

BACKGROUND Loperamide is used as an antidiarrheal drug and is available over-the-counter. It cannot pass the blood-brain barrier and it does not have a considerable abuse potential. It can lead to dangerous cardiac arrhythmia. CASE REPORT Herein, we report a 35-year-old man with a 13-year history of abusing opioids who had undergone detoxification for four times during this period. He underwe...

Maternal substance abuse is the most common factor involved when children come to the attention of the child welfare system. Although there is a clear need for clinical trials to evaluate parenting interventions for drug-dependent women, few studies to date have systematically examined the efficacy of interventions for this population. We first review six published reports of outpatient interve...

Work on this instrument grew out of research on newborn assessment and training for the Perinatal-20 project, a set of 20 National Institute on Drug Abuse (NIDA)-sponsored intervention studies of cocaineand other substance-abusing mothers, and the specific requirements of research on the Maternal Lifestyles Study, a National Institute of Child Health and Human Development-sponsored multisite st...

Acts of violence include bullying, verbal threats, physical assault, domestic abuse, the use of objects or weapons to harm another, and gunfire. Premature death, disability, and academic failure occur due to the violent activity that surrounds many American youth. Risk factors that contribute to youth violence include a history of being abused or abusing others, school truancy, poor time use, e...

This study examined aggressive behaviors in the adolescent children of HIV-positive and HIV-negative drug-abusing fathers. Data were collected via individual structured interviews of low-income, predominantly African American and Hispanic, father-child dyads (N = 415). Structural Equation Modeling was used to assess the interrelationship of several latent constructs with respect to adolescent a...

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Although HIV prevention during substance abuse treatment is ideal, existing HIV riskreduction interventions are less effective among Black and other ethnic minority substance abusers. The Sexual Health Model (SHM) and the Person, Extended Family and Neighborhood-3 model (PEN-3) both highlight the importance of increasing our understanding of the relationship of sociocultural factors to sexual-d...