We reviewed the clinical and laboratory oculomotor features in 30 patients with probable multiple system atrophy (MSA), 22 with MSA-P and 8 with MSA-C. Six patients were also examined post mortem, MSA being confirmed in four and excluded in two (Parkinson's disease and progressive supranuclear palsy). Clinical examination showed the following abnormalities; excessive square wave jerks--21 of 30...

purpose: to describe three cases of exotropic mobius syndrome and to report outcomes of the surgical intervention. case reports: three patients including two boys and one girl were referred to our strabismus clinic. all had masked faces and non-progressive congenital bilateral facial palsy and dry eye. other abnormalities included large angle exotropia and bilateral horizontal gaze palsy. surgi...

Postural instability and supranuclear gaze palsy represent the key symptoms of Richardson's syndrome, the most frequent clinical manifestation of progressive supranuclear palsy (PSP). However, a proportion of PSP patients never develops ocular motor symptoms, which prevents clinicians from establishing the diagnosis during lifetime according to current diagnostic criteria. We present one instru...

A 51-year-old woman with breast cancer presented with progressive diplopia. Neuro-ophthalmologic examination revealed right gaze palsy and peripheral facial nerve palsy. Brain magnetic resonance imaging (MRI) was normal. However, two months later a repeat brain MRI revealed an enhancing round nodular mass at the right facial colliculus of the lower pons, at the location of the abducens nucleus....

We examined the changes in Listing's plane resulting from prismatically induced vergence. The three-dimensional angular positions of the two eyes were compared in normal subjects wearing search coils and gazing at targets 1.9 m away with and without prisms. For horizontal base-out prisms each degree of convergence in one eye yielded 0.72 deg of temporal rotation of Listing's plane in that eye. ...

In a sibship of 11, two brothers with a congenital complete horizontal gaze palsy developed severe kyphoscoliosis. No-one else in the family has a gaze palsy or comparable skeletal abnormalities. Since the parents are first cousins, an autosomal recessive mode of inheritance seems likely.

The purpose of this study was to evaluate the effect of galvanic vestibular stimulation (GVS) on recovery from gaze palsy. Twenty patients with gaze palsy, (14 males and 6 females) their age ranged from 20–63 years with mean age 47.9±12.5 years. Duration of gaze palsy ranged from 4–24 months with mean of 10.6±5.23. Twelve patients were post stroke and eight patients with definite multiple scler...

Claude's syndrome caused by dorsal midbrain lesion is characterized by ipsilateral third nerve palsy and contralateral ataxia. To date, reports in the literature concerning Claude's syndrome associated with the midbrain paresis of horizontal gaze are rare. A 62-year-old man suddenly developed left third cranial nerve palsy, right lateral gaze palsy, and right ataxia. Intact Bell's phenomenon an...