Binary fatty acid mixture-based solid lipid nanoparticles (SLNs) were prepared for delivery of diacerein, a novel disease-modifying osteoarthritis drug, with and without simultaneously loaded gold nanoparticles (GNPs). In order to optimize SLNs for temperature-responsive release, lipid mixtures were prepared using different ratios of solid (stearic acid or lauric acid) and liquid (oleic acid) f...

The solvent evaporation method on the structural changes and surface chemistry of the cathode and the effect of electrochemical performance of Li1.0Ni0.8Co0.15Mn0.05O2 (NCM) has been investigated. After dissolving of Li residuals using minimum content of solvent in order to minimize the damage of pristine material and the evaporation time, the solvent was evaporated without filtering and remain...

The present work was aimed to develop and characterize rosuvastatin loaded self emulsifying drug delivery system for the effective management of hypolipidemia (RSEDDS) for improving bioavailability, to enhance solubility, to prolong residence time and to provide sufficient amount of drug to a target site in a sustained release manner. Self-emulsifying drug delivery system was prepared by simple...

Nanostructuring of drug delivery systems offers many promising applications like precise control of dissolution and release kinetics, enhanced activities, flexibility in terms of surface coatings, integration into implants, designing the appropriate scaffolds or even integrating into microelectronic chips etc. for different desired applications. In general such kind of structuring is difficult ...

In this study, Analytical Hierarchy Process (AHP) was employed to select the best method for the preparation of Nateglinide (NTG)loaded nanoparticles. There are various techniques available for the development of nanoparticles like Nanoprecipitation or Solvent displacement, Ionic gelation, Solvent evaporation method etc. and choosing the best method is a crucial one. AHP is one of the widely us...

Single Crystals of L-lysine sulphate (abbreviated as LLS), a semiorganic nonlinear (NLO) materials have been successfully grown by slow solvent evaporation solution growth technique at room temperature. Solubility curve of LLS has been determined in mixed solvent of acetone and water. The grown crystal is characterized by single crystal X-ray diffraction (XRD) and Fourier transform infrared spe...

double emulsion solvent evaporation technique is one of the most attractive methods used to prepare micro and nanoparticles in pharmaceutical areas of interest, but because of the effects of many formulation factors on the size and release behavior of the fabricated particles, optimization of the formulation factors is needed. in this study various parameters including technical and composition...

Objective: The main purpose of this study is to prepare a floating micro articulated drug delivery system of ciprofloxacin by using non-aqueous solvent evaporation technique to increase the bioavailability and therapeutic effectiveness of the drug by prolonging its gastric residence time. Methods: Floating microparticles were prepared by using different low-density polymers such as ethyl cellul...