The purpose of this investigation was to evaluate the potential dosimetric benefits of a two-phase adaptive intensity-modulated radiotherapy (IMRT) protocol for patients with locally advanced nasopharyngeal cancer (NPC). A total of 17 patients with locally advanced NPC treated with IMRT had a second computed tomography (CT) scan after 17 fractions in order to apply and continue the treatment wi...

PURPOSE Intensity modulated radiation therapy (IMRT) treatment plan quality depends on the planner's level of experience and the amount of time the planner invests in developing the plan. Planners often unwittingly accept plans when further sparing of the organs at risk (OARs) is possible. The authors propose a method of IMRT treatment plan quality control that helps planners to evaluate the do...

background ankle injuries are one of the most common presentations in emergency department. ottawa ankle rules (oars) have been used to predict the requirement of radiographs. objectives this study aimed to validate the oars protocol for predicting ankle and midfoot fractures in indian population. patients and methods a prospective study was conducted in a teaching hospital in north india, duri...

PURPOSE For patients undergoing external beam radiation therapy (EBRT) and brachytherapy, recommendations for target doses and constraints are based on calculation of the equivalent dose in 2 Gy fractions (EQD2) from each phase. At present, the EBRT dose distribution is assumed to be uniform throughout the pelvis. We performed a preliminary study to determine whether deformable dose distributio...

Abstract BACKGROUND Craniospinal irradiation (CSI) is indicated for adult patients diagnosed with leptomeningeal disease (LMD). Proton-based vertebral-body-sparing (VBS) CSI has been explored pediatric to minimize hematologic toxicity; however, utilization of VBS in an population limited. We hypothesize that VBS-CSI utilizing volumetric modulated arc therapy (VMAT) will effectively reduce verte...

BACKGROUND To investigate the feasibility and benefits of a modified adaptive radiotherapy (ART) by replanning in the initial CT (iCT) with new contours from a repeat CT (rCT) based on CT-CT image fusion for nasopharyngeal cancer (NPC) patients underwent volumetric modulated arc radiotherapy (VMAT). MATERIALS AND METHODS Nine NPC patients underwent VMAT treatment with a rCT at 23rd fraction w...

PURPOSE Tomotherapy for intensity-modulated radiation has been demonstrated to reduce unnecessary irradiations to adjacent organs at risk (OARs). The purpose of this study was to compare the dosimetric parameters between Tomotherapy and three-dimensional conformal radiotherapy (3D-CRT) in rectal cancer patients. MATERIALS AND METHODS We redesigned three-dimensional conformal plans for 20 rect...

Although the Manchester system is still extensively used to prescribe dose in brachytherapy (BT) for locally advanced cervix cancer, many radiation oncology centers are transitioning to 3D image-guided BT, owing to the excellent anatomy definition offered by modern imaging modalities. As automatic dose optimization is highly desirable for 3D image-based BT, this study comparatively evaluates th...

PurposeTumor and anatomical changes during radiotherapy have been observed in stage III non-small cell lung cancer (NSCLC) from many previous studies. We hypothesized that a routinely scheduled adaptive would clinical important dose benefits to lower the risk of toxicities, without increasing tumor recurrences.MethodsWe retrospectively reviewed 92 consecutive patients with inoperable NSCLC betw...