The precise calibration of the strain readout LIGO gravitational wave observatories is paramount to accurate interpretation events. This traditionally done by imparting a known force on test masses observatory via radiation pressure. Here, we describe implementation an alternative scheme: Newtonian calibrator. system uses rotor consisting both quadrupole and hexapole mass distributions apply ti...

UNLABELLED In the framework of a Dutch project named "Calibration 2000" harmonization of antithrombin activity assays was studied. The commutability of potential calibrators for antithrombin was assessed by means of a twin-study design, which is a multicentre, split-patient sample, between-field-methods protocol. The twin-study consisted of simultaneous analysis of fresh-frozen patient plasmas ...

In a Dutch project for harmonization of fibrinogen assays, the commutability of potential calibrators for fibrinogen was assessed by means of a twin-study design, which is, in essence, a multicentre, split-patient sample, between-field-methods protocol. The study consisted of simultaneous analysis of fresh-frozen patient plasmas and three potential calibrators for fibrinogen by 48 Dutch laborat...

The presence of antibodies (Abs) in hemophilia A patients can potentially influence the therapeutic qualities of factor VIII (fVIII) administration. Much work has been focused on the presence of inhibitory antibodies, whereas the quantitation of noninhibitory anti-fVIII antibodies has been largely undetermined. Our objective was to develop a sensitive and specific fluorescencebased immunoassay ...

We report a competitive reverse transcriptase-PCR (RT-PCR) assay and a calibrated user-friendly RT-PCR assay (CURT-PCR) for epidermal growth factor receptor (EGFR) mRNA. A calibrator was prepared from isolated rat liver RNA, and the amount of EGFR mRNA was determined by competitive RT-PCR. In CURT-PCR, a calibration curve was developed by plotting the ratio between the amount of PCR product ori...

BACKGROUND Despite the increasing use of real-time PCR in the diagnosis and management of viral infections, there are no published studies adequately addressing the optimum number of calibrators, the number of replicates of each calibrator, and the frequency with which calibration needs to be repeated. This study was designed to address these issues. METHODS Cycle threshold data (ABI 7700) wa...

OBJECTIVES Haptoglobin (Hp) phenotypes 1-1, 2-1, and 2-2 are associated with inflammatory diseases. Since their biochemical structures are rather heterogeneous, it is necessary to accurately determine the plasma Hp levels. DESIGN AND METHODS Immunodiffusion, immunoturbidimetric, and noncompetitive ELISA were conducted to determine the differences in immunoreactivity among Hp phenotypes and to...

Critical measurement performance of fluid flowmeters requires proper and quantified verification data. These data should be generated using calibration and traceability techniques established for these verification purposes. In these calibration techniques, the calibration facility should be well-characterized and its components and performance properly traced to pertinent higher standards. The...

This paper presents the third extension to the Very Large Baseline Array (VLBA) Calibrator Survey, containing 360 new sources not previously observed with very long baseline interferometry (VLBI). The survey, based on three 24 hour VLBA observing sessions, fills the areas on the sky above declination −45 where the calibrator density is less than one source within a 4 radius disk at any given di...

This paper presents the fifth part of the Very Long Baseline Array (VLBA) Calibrator Survey (VCS), containing 569 sources not observed previously with very long baseline interferometry in geodetic or absolute astrometry programs. This campaign has two goals: (i) to observe additional sources which, together with previous survey results, form a complete sample, (ii) to find new strong sources su...