introduction: acute leukemia covers a broad spectrum of hematological clonal diseases originating from the malignant transformation of stem cells. current chemotherapeutic methods result in an incomplete response to primary regimens in 30-40% of cases. methods: 20 patients who had been diagnosed with acute leukemia and who had displayed defined criteria in order to enter our study, were assesse...

In pigs it is used for treatment of dysenteria due to Serpulina hyodysenteriae at a dosage of 25 mg/kg/day for 4 days for therapy. For eradication of the disease in herds treatment for 7 days and a second treatment period of 5 days after 3-4 weeks is indicated. Metronidazole is intended for use in cows with retentio secundinarum in combination with neomycine administered as intra-uterine capsul...

In a double-blind study the advantages of a once-a-day dosage of a tricyclic antidepressant as against a thrice daily dosage regimen was evaluated using dothiepin (Prothiaden) and matching placebo tablets. Twenty eight adult patients of both sexes participated in the study and were randomly allocated to drug treatment. Out of 28 patients who received dothiepin, 17 showed good improvement, in 6 ...

Analysis of the response to corticosteroid therapy in a personal series of 8 consecutive cases of dermatomyositis in childhood shows that there are advantages in a moderate dosage, short-term treatment schedule, with gradual tapering of the dosage as soon as there is clinical improvement without waiting for full remission, and in trying to stop steroid therapy within six months rather than foll...