Abstract We wrote and used an automated flare detection Python script to search for super-flares on main sequence stars of types A, F, G, K M in Kepler’s long-cadence data from Q0 Q17. studied the statistical properties occurrence rate super-flares. For G-type set, we compared our results with previous Okamoto et al. by splitting set into four rotational bands. found similar power-law indices f...

OBJECTIVE We investigated the comparative roles of mitogen-activated protein (MAP) kinases, including c-Jun NH2-terminal kinase (JNK), extracellular signal-regulated kinase (ERK), and p38, in vascular smooth muscle cell (VSMC) proliferation, migration, and gene expression. METHODS AND RESULTS VSMCs were infected with recombinant adenovirus containing dominant-negative mutants of ERK, p38, and...

We consider presentations that were derived in [3] for the interval groups associated with proper quasi-Coxeter elements of Coxeter group W(Dn). use combinatorial methods to derive alternative groups, and these new show a element W(Dn) cannot be isomorphic Artin type Dn. While specific problems we solve arise from study their solution provides an illustration how techniques indicated by computa...

14-3-3 family members are dimeric phosphoserine-binding proteins that regulate signal transduction, apoptotic, and checkpoint control pathways. Targeted expression of dominant-negative 14-3-3eta (DN-14-3-3) to murine postnatal cardiac tissue potentiates Ask1, c-jun N-terminal kinase (JNK), and p38 mitogen-activated protein kinase (MAPK) activation. DN-14-3-3 mice are unable to compensate for pr...

Diabetic nephropathy (DN), which is a major end-organ complication in diabetes, continues to be the most common cause of end-stage renal disease and accounts for .40% of patients on renal replacement therapy (1). Currently available factors that are routinely used in clinical practice to predict and monitor the progression of DN include degree of proteinuria and both glycemic and blood pressure...

A molecular mechanism is proposed for the toughness enhancement observed in double-network (DN) hydrogels prepared from poly(2-acrylamido-2-methyl-1-propanesulfonic acid) (PAMPS) polyelectrolyte network and poly(acrylamide) (PAAm) linear polymer. It is an extension of the phenomenological model set forth recently by Gong et al. ( Macromolecules 2007, 40, 6658- 6664 ). This mechanism rationalize...

Nutrient losses from headwater catchments (<50 km2) cause eutrophication problems downstream. Catchment properties are strongly reflected in the levels of nutrient concentrations streams. Based on measurements total and dissolved nitrogen (TN, DN) phosphorus (TP, DP) 235 small streams, we showed that proportion arable land a catchment had strongest positive effect concentrations, with coefficie...

Diabetic nephropathy (DN) is one of the most serious chronic microvascular abnormalities diabetes mellitus and major cause uremia. Accumulating evidence has confirmed that fibrosis a significant pathological feature contributes to development kidney disease in DN. However, exact mechanism renal DN still unclear, which greatly hinders treatment Chinese herbal medicine (CHM) shown efficacy safety...

BACKGROUND Diabetic neuropathy (DN) is a common complication of diabetes that has significant economic burden, especially for patients with comorbid depression or anxiety. This study examines and quantifies factors associated with healthcare costs among patients diagnosed with diabetic neuropathy (DN) with or without a comorbid diagnosis of depression or anxiety (DA) using retrospective adminis...