Purpose Real-life clinical outcomes of patients treated with anti-VEGF drugs for neovascular age-related macular degeneration (nAMD), diabetic macular edema (DME), or macular edema secondary to branch retinal vein occlusion (BRVO) are often inferior to results from randomized clinical trials. This observational cohort study investigates treatment adherence and real-life clinical outcomes within...

Tungsten NArR alkylidene complexes have been prepared that contain the electron-withdrawing ArR groups 2,4,6-X3C6H2 (ArX3, X = Cl, Br), 2,6-Cl2-4-CF3C6H2 (ArCl2CF3), and 3,5-(CF3)2C6H3 (Ar(CF3)2). Reported complexes include W(NArR)2Cl2(dme) (dme = 1,2-dimethoxyethane), W(NArR)2(CH2CMe3)2, W(NArR)(CHCMe3)(OTf)2(dme), and W(NArR)(CHCMe3)(ODBMP)2 (DBMP = 4-Me-2,6-(CHPh2)C6H2). The W(NArR)(CHCMe3)(...

We analyse the formation of He I lines in late-type dwarfs by statistical equilibrium (or NLTE radiative transfer) computations. Atmospheric models for dK (Eri) and dMe V1005Ori (=Gl 182) stars are considered. The validity of the weakly non-uniform approximation for dMe stars established in Lanzafame (1994a) for the lower transition region of dMe stars implies that streaming particles have virt...

BACKGROUND How patients are informed regarding their choices of durable medical equipment (DME) providers for home-going respiratory equipment may affect their decisions about which vendor to use. When a new enhanced information program to inform home-going patients about all available respiratory DME providers was implemented, we hypothesized that patients' utilization of providers would chang...

INTRODUCTION Laser photocoagulation has been the standard treatment for diabetic macular edema (DME) and proliferative diabetic retinopathy (PDR) for several decades. The discovery of vascular endothelial growth factor (VEGF) and the subsequent determination of its critical role in the development DME and PDR has led to the development of VEGF inhibitory drugs. Ranibizumab was the first anti-VE...

BACKGROUND The short-term effects of intravitreal ranibizumab (IVR) on diabetic macular edema (DME) remains unclear. We assessed the short-term effects of IVR on DME. METHODS Eighteen eyes of 14 patients with DME were enrolled in this prospective interventional case series. After intravitreal ranibizumab was injected into treatment-naïve eyes with DME, we measured the foveal thickness (FT) be...

Diabetic retinopathy is the leading cause of blindness among individuals of working age in industrialized nations, with most of the vision loss resulting from diabetic macular edema (DME). The formation of DME depends on the action of several growth factors and inflammatory mediators, but vascular endothelial growth factor (VEGF) appears to be critical for breaking down the blood-retinal barrie...

The identity and reversibility of the elementary steps required for catalytic combustion of dimethyl ether (DME) on Pt clusters were determined by combining isotopic and kinetic analyses with density functional theory estimates of reaction energies and activation barriers to probe the lowest energy paths. Reaction rates are limited by C-H bond activation in DME molecules adsorbed on surfaces of...

The Stretched-FrOnt-Leg (SFOL) pulse is a high-accuracy distance measuring equipment (DME) developed to support alternative positioning and navigation for aircraft during global satellite system outages. To facilitate the use of SFOL pulse, it best legacy DMEs that are already deployed transmit rather than current Gaussian through software changes only. When attempting in DMEs, greatest challen...

Solvent-driven water extraction (SDWE) has promising applications in hypersaline brine desalination, including zero-liquid discharge processing for industrial wastewaters, and resource recovery, such as the of lithium rare earth elements from solution mining leachates. In this study, we develop a computational thermodynamic framework to analyze liquid–liquid brines using dimethyl ether (DME), a...