Fast dissolving film of levocetrizine dihydrochloride were prepared by solvent casting method by using Maltodextrin & HPMC E15 as the main film forming polymers.To decrease the disintegration time,concentration of maltodextrin & HPMC E15 were optimized be using 2 factorial design. Disintegration time, drug release pattern, mouth dissolving time and content uniformity were also evaluated. Compat...

BACKGROUND/AIM Switching the patient from one pharmaceutical formulation of the same drug to another, may lead to therapeutic inadequancy in some cases. To minimize the risk, careful pharmacokinetic studies are desired in the pre-registration period and afterwards. METHODS A randomized, crossover design with one-week wash-out period between each dose was applied. Serum samples, obtained befor...

Blue native gel electrophoresis (BN-PAGE) is used extensively for characterization of mitochondrial respiratory complexes and uses the binding of Coomassie brilliant blue G-250 to visualize proteins. Oxidative modification of sulfhydryl groups of such proteins can be evaluated by labeling with iodoacetamide conjugated to biotin (BIAM) and detected with streptavidin peroxidase on Western blots f...

Using ultrasonic devices in endodontics can enhance the antibacterial and tissue dissolving ability of different root canal irrigants such as sodium hypochlorite (NaOCl) which is the most common irrigant with excellent antibacterial and tissue dissolving abilities. However, due to its high surface tension, its penetration into the irregularities of the root canal system is a challenge. The purp...

Implantation of silicon wafers with Ga and P, under specific conditions, results in enhanced category-II (end of range) dislocation loop elimination after short thermal cycling. Comparison of these results with transmission electron microscopy studies of Si-, Ge-, As-, AI-, and Sb-implanted samples indicate that the enhanced elimination process occurs only when the peak of the impurity concentr...

A reactive fluid dissolving a uniform porous material triggers an instability in the dissolution front, leading to spontaneous formation of pronounced well-spaced channels in the surrounding rock matrix. The concentration field within the dissolving region contains two different length scales, upstream (no reaction) and downstream of the front position. Previous investigations of the reaction-i...

In the present investigation, the abundance and molecular phylogeny of part of the culturable bacterial population involved in the dissolution of "miliolite", a bioclastic limestone, from Gopnath, India, was studied. Carbonate-dissolving bacteria were isolated, enumerated and screened for their ability to dissolve miliolite. Amplified ribosomal DNA restriction analysis (ARDRA) indicated 14 oper...

Enzymatic treatment of different sulphite pulps with cellulases has been studied in this work. Endoglucanases were shown to beneficially alter the properties of both paper-grade and dissolving-grade pulps. In the case of the paper-grade pulp, the treatment with endoglucanase resulted in a considerable reduction of the pulp refining time without decrease in strength properties. While for the dis...

This paper looks at the use of techniques to prevent the communication of steganographic data by filtering. These filters are broken into two categories; Overwriting and Dissolving. Overwriting can be defined as being the effective implementation of a Steganographic message over the original message. Dissolving can be defined as being modifications to the picture in order to prevent the decodi...

By modeling mass transfer phenomena, we simulate solids and liquids dissolving or changing to other substances. We also deal with the very small-scale phenomena that occur when a fluid spreads out at the interface of another fluid. We model the pressure at the interfaces between fluids with Darcy’s Law and represent the viscous fingering phenomenon in which a fluid interface spreads out with a ...