Multiple benign osteolytic lesions are very hard to differentiate from disseminated bone metastasis. Whole-body bone scintigraphy (WBBS) with technetium-99m methylene diphosphonate (Tc-99m MDP) demonstrates multiple lesions with increased uptake in any bone involved. Even combined with medical history and multiple imaging results, such as MRI and CT, the clinical diagnosis of metastasis lesion ...

BACKGROUND AND OBJECTIVE To date, reports on the safe and effective laser treatment of disseminated granuloma annulare (GA) are still limited. STUDY DESIGN/PATIENT AND METHODS A 58-year-old Caucasian female with disseminated GA was treated with fractional photothermolysis (FP) using a 1,440-nm Nd:YAG laser. Four lesions on the patient's left upper arm were defined as the "test region" with th...

This review provides a comprehensive overview of the broad clinicopathologic spectrum of cutaneous Kaposi sarcoma (KS) lesions. Variants discussed include: usual KS lesions associated with disease progression (i.e. patch, plaque and nodular stage); morphologic subtypes alluded to in the older literature such as anaplastic and telangiectatic KS, as well as several lymphedematous variants; and nu...

L’endoscope s’est imposé comme une valeur sûre en chirurgie oro-maxillo-faciale. Outre les interventions sur l’articulation temporo-mandibulaire, il est utilisé de manière routinière traumatologie et des sinus paranasaux.

1. Ecole Normale Supérieure, INSERM U960 and Université Paris 6, Paris, F-75005, France. 2. AP-HP, Hôpital Beaujon, Service d’ORL et Chirurgie Cervico-Faciale, Clichy, F-92110, France. 3. Hallym University College of Medicine, Department of Otorhinolaryngology-Head and Neck Surgery, 896, Pyeongchon-dong, Dongan-gu, Anyang-si, Gyeonggi-do, 431-070, Republic of Korea. 4. Hospices Civils de Lyon, ...

IFN-gamma releasing assays (IGRAs) such as T-SPOT.TB assay and QuantiFERON-TB In-Tube (QFT-GIT) have yielded promising results for the diagnosis of tuberculosis (TB). However, little is known about the usefulness of these assays for diagnosing disseminated TB. We therefore compared their usefulness with traditional tests in patients with disseminated TB. All adult patients with suspected dissem...

Rational discovery of novel immunodiagnostic and vaccine candidate antigens to control bovine tuberculosis (bTB) requires knowledge of disease immunopathogenesis. However, there remains a paucity of information on the Mycobacterium bovis-host immune interactions during the natural infection. Analysis of 247 naturally PPD+ M. bovis-infected cattle revealed that 92% (n = 228) of these animals wer...

Affiliations: Normandie Univ, UNIROUEN, Rouen, France, and Institute for Research and Innovation in Biomedicine (IRIB), Rouen, France. Pôle 3R, Rouen University Hospital, Rouen, France. CRMPR les Herbiers, Bois Guillaume, France. European Society for Swallowing Disorders, Canet de Mar, Spain. Unitat d’ Exploracions Funcionals Digestives, Department of Surgery, Hospital de Mataró, Universitat Au...