Cryoelectron tomography opens a window into the inner space of cells. It combines the potential of three-dimensional imaging with a close-to-life preservation of biological samples. Tomograms with molecular resolution are essentially images of the cellular proteome and, in conjunction with advanced pattern recognition techniques, they can be used to map the molecular landscape inside organelles...

An automated method to register three-dimensional Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) brain images is presented. In a first step, mathematically well founded differential operators in scale space are applied to 2D or 3D CT and MRI images resulting in feature images depicting ’ridgeness’. In a second step, a fully automatic hierarchical correlation scheme is applied to ...

BACKGROUND Advances in three-dimensional imaging and three-dimensional printing technology have expanded the frontier of presurgical design for microtia reconstruction from two-dimensional curved lines to three-dimensional perspectives. This study presents an algorithm for combining three-dimensional surface imaging, computer-assisted design, and three-dimensional printing to create patient-spe...

We present an adult patient who had an acute myocardial infarction complicated by a ventricular septal defect and had it repaired percutaneously. Real-time three-dimensional echocardiography (RT3D) before and during the closure procedure were performed. RT3D provided anatomical and functional information of the defect as well as real-time guidance during the procedure. This case highlights the ...

A total-variation-minimization-based iterative algorithm is describ ed in this paper that enhances the quality of reconstructed images with time-domain data over that obtained previously with a regularized least-squares approach. ©2010 Optical Society of America OCIS codes: (110.6960) Tomography; (110.5120) Photoacoustic imaging

Ventilation distribution calculation using 4D CT has shown promising potential in several clinical applications. This study evaluated the direct geometric ventilation calculation method, namely the ΔV method, with xenon-enhanced CT (XeCT) ventilation data from four sheep, and compared it with two other published meth-ods, the Jacobian and the Hounsfield unit (HU) methods. Spearman correlation c...

The aim of this study was to reveal biometric peculiarities of New Zealand white rabbit antebrachium (radius and ulna) by means of three-dimensional (3D) reconstruction of multidetector computed tomography (MDCT) images. Under general anesthesia, the antebrachiums of a total of sixteen rabbits of both sexes were scanned with a general diagnostic MDCT. Biometric measurements of the reconstructed...