In this study, we focused on diffuse reflectance spectroscopy, a rapid and noninvasive spectroscopy technique that has considerable potential for medical diagnosis. order to better understand analyze the signals induced by method, performed series of in vivo measurements healthy diseased skin. Measurement sites human hand feet were chosen. Some preliminary results obtained these show feasibilit...

geothermal investors need to be confident with the methods and results of exploration programs. also cutting the upfront cost of geothermal exploration will further encourage investors to consider investment in this emerging clean energy field. hence, it is of paramount importance to improve prospecting techniques in order to explore where economic concentrations of geothermal energy are to be ...

OBJECTIVES Investigate the use of optical reflectance spectroscopy to differentiate malignant and nonmalignant tissues in head and neck lesions and characterize corresponding oxygen tissue biomarkers that are associated with pathologic diagnosis. STUDY DESIGN Cross-sectional study. SETTING Tertiary Veterans Administration Medical Center. SUBJECTS AND METHODS All patients undergoing panend...

We report on the development of an integrated point-wise spectroscopy and autofluorescence (AF) endoscopic imaging technique for real-time in vivo tissue measurements at endoscopy. We implement a unique point spectrum optical design to realize real-time AF imaging and AF or diffuse reflectance (DR) spectroscopy measurements from a small area of tissue of interest on the AF image. We demonstrate...

BACKGROUND Diffuse reflectance spectroscopy (DRS) uses the steady-state diffuse reflectance measured from the tissue surface to determine absorption and scattering properties of sampled tissue. Many inverse models used to determine absorber properties have assumed a homogeneous distribution of blood. However, blood in tissue is confined to blood vessels that occupy a small fraction of the overa...

BACKGROUND AND OBJECTIVES Mechanical indentation has been shown to increase light transmission through turbid tissue. In this study, we investigated the effects of localized indentation on the optical properties of ex vivo porcine skin specimens by dynamically monitoring diffuse reflectance spectra, light transmission, and applied load while controlling tissue thickness. STUDY DESIGN/METHODS ...