invasive aspergillosis is one the major causes of death in hematopoietic and solidtransplantrecipients. one of the most critical problems in medical mycology is theinability to consistently make a convincing and early diagnosis of invasive fungalinfection. conventional diagnosis methods such as culture-based approaches are limitedby the insufficient accessibility sensitivity and the non-culture...

introduction: the most common chromosomal abnormalities detected in perinatal period are aneuploidies of chromosome 21, 18, 13, x and y. the aim of this study is to assess referral reasons for invasive diagnostic method using rapid qf-pcr for fetal chromosomal abnormalities in gynecologists’ referrals. methods: a retrospective study of results was performed on data between september 2015 and ju...

midgut malrotation is typically presented during the first few months of life but sometimes may encounter later in life, causing difficulties and mistakes in diagnosis. we reviewed records of eleven rare patients with midgut malrotation older than one year of age and extracted their clinical and paraclinical data. the most common presenting symptoms were bilious vomiting, recurrent abdominal pa...

it is estimated that the number of hiv infected children globally has increased from 1.6 million in 2001 to 3.3 million in 2012. the number of children below 15 years of age living with hiv has increased worldwide. published data from recent studies confirmed dramatic survival benefit for infants started anti-retroviral therapy (art) as early as possible after diagnosis of hi. early confirmatio...

community-acquired pneumonia and brucellosis are of the main agents causing mortality in the world. the most important limitations for the identification of these agents include their high resistance against environmental conditions, impossibility of rapid and on time diagnosis, low level of infective dose, and lack of existence of vaccine against many types of them. hence, on time action and d...

currently, different highly sensitive nucleic acid detection-based protocols used in medical diagnostic laboratories need specific working conditions, and if no optimization is performed, misleading results can be obtained. limitations of each protocol is different in obtaining an appropriate result. awareness of these limitations plays an important role in providing a reliable result for physi...

background and aims. the aim of the present study was to compare the effect of application of an image processing mode of a colorizer on the efficacy of the detection of interproximal carious lesions viewed in direct digital radiography. materials and methods. a total of 102 proximal surfaces of extracted human premolars on direct digital images were evaluated by three observers with and withou...

a sensitive monitoring of biological analytes, such as biomolecules (protein, lipid, dna and rna), and biological cells (blood cell, virus and bacteria), is essential to assess and avoid risks for human health. nanobiosensors, analytical devices that combine a biologically sensitive element with a nanostructured transducer, are being widely used for molecular detection of biomarkers associated ...

conclusions development of novel drugs and diagnostic tests has allowed us to better manage vl. although leishmaniasis is one of the oldest known parasitic infectious diseases, increasing prevalence of vl among specific populations, recent reports of disease reactivation and flare-up in clinically asymptomatic patients after the onset of immunosuppressive therapy, the risk of disease acquisitio...

celiac disease is a chronic, systemic and autoimmune disorder of gastrointestinal track that involves approximately 1% of individuals of all ages throughout the world. the collaboration of environmental factor such as gluten proteins and genetic factors, notably hla-dq2 and/or hla-dq8 trigger the disease. gluten-free diet is the simply and merely safe and proficient existing treatment. this art...