Objective(s):Many studies have reported that tea consumption decreases cardiovascular risk, but the mechanisms remain unclear. Green tea is known to have potent antioxidant and free radical scavengingactivities. This study aimed to investigate whether green tea extract (GTE) can protect endothelial progenitors cells (EPCs) against oxidative stress through antioxidant mechanisms. Materials and M...

Introduction: Trimethyltin (TMT) is a short-chain trialkyltin used as a stabilizer of plastics. It is also a known neurotoxic agent in both human and animals. Clavulanic acid is previously known as a non-competitive inhibitor of β-lactamase. Oral bioavailability, low antibiotic activity and good CNS penetration are important properties of CA which nominated this compound for evaluation neu...

Iron(III) complexes of curcumin (Hcur) having a tridentate NNN-donor dipicolylamine-based ligand L1 and its biotinylated analogue L2, namely, [Fe(L1)(cur)Cl] (1) [Fe(L2)(cur)Cl] (2), were prepared, characterized their photo-induced cytotoxicity studied. The exhibited curcumin-based absorption band near 430 nm emission maxima at 520 nm. Complex 2 with biotin moiety showed enhanced cellular uptak...

Gap junctions are intercellular channels that connect the interiors of coupled cells. We sought to determine the extent to which malignant glioma cells form gap junction channels with astrocytes from either adult human brain or rat forebrain. The astrocytic gap junction protein, connexin 43 (Cx43), was identified in immunoreactive plaques at areas of cell-to-cell contact between cocultured glio...

objective(s):many studies have reported that tea consumption decreases cardiovascular risk, but the mechanisms remain unclear. green tea is known to have potent antioxidant and free radical scavengingactivities. this study aimed to investigate whether green tea extract (gte) can protect endothelial progenitors cells (epcs) against oxidative stress through antioxidant mechanisms. materials and m...

Abelmoschus esculentus (Okra) is used in the traditional treatment of cancer, hyperlipidaemia and hyperglycaemia. We, therefore, investigated its composition potential cytotoxic or antioxidant properties that might underlie phytotherapeutic applications. Its methanolic fruit extract yielded compounds 1, 2 3, identified through NMR, UV MS analyses as olean-12-en-3-O-β-d-glucopyranoside, isoquerc...

conclusions in our study, no prominent effect was seen; therefore, in order to have a better perspective of crocin activity against cancerous cell lines, further studies are highly recommended. results the highest concentration of crocin significantly decreased ros production after 48 hours of treatment. however, crocin had no effect on the expression level of hsp (heat shock protein). addition...

Chapter 1. An Introduction to Fluorescent Zn(II) Sensors and Their Applications in Biological Systems This chapter opens with an overview of the numerous roles of zinc in biology, with an emphasis on labile Zn(II), that is, loosely bound or kinetically available stores of the ion. The synthesis, characterization, and application of fluorescent sensors for Zn(II) detection constitute an active f...

Abstract. Several automated instruments exist to measure the acellular oxidative potential (OP) of ambient particulate matter (PM). However, cellular OP PM is still measured manually, which severely limits comparison between two types assays. Cellular assays could provide a more comprehensive assessment PM-induced stress, as they incorporate biological processes involved in PM-catalyzed reactiv...