BACKGROUND End-stage renal disease (ESRD) patients exhibit an extraordinarily high annual mortality secondary to cardiac and vascular causes, particularly sudden cardiac death (SCD). Left ventricular (LV) hypertrophy is a frequent finding and constitutes an independent predictor of mortality risk in these patients. Mineralocorticoid receptor antagonists (MRAs) are cardioprotective in heart fail...

Annual influenza vaccination is recommended, but its efficacy in dialysis population is still controversial. Here we aimed to compare the dynamic changes of immune response between various influenza vaccination protocols in hemodialysis patients. A 18-week open label, non-randomized, controlled trial was conducted during 2011-2012. The efficacy between unvaccinated, one- and two-dose regimens w...

BACKGROUND Most patients with end-stage renal disease require dialysis to survive because they are unable to access kidney transplantation. Peritoneal dialysis (PD) is recommended by some clinical practice guidelines as the dialysis treatment of choice for adults without significant comorbid conditions or those with residual kidney function. This study aims to synthesize published qualitative s...

background: peritoneal dialysis is one of the most prevalent types of dialysis prescribed to the patients suffering from renal failure. studies on the factors affecting the survival of these patients have mainly used log-rank test and cox analysis. the present study aimed to investigate the risk factors affecting short- and long term survival of patients on continuous ambulatory peritoneal dial...

results out of 66 patients, 61 (19 in group a, 20 in group b, and 22 in group c) completed the study period, and before intervention, all groups were equal in terms of quality and quantity variables (p > 0.05). after intervention, there was a significant difference between the three groups with regard to the variables of dialysis adequacy based on kt/v and urr to independent-t test and repeated...

BACKGROUND Despite many advantages over facility-based therapies, less than 25 % of prevalent dialysis patients in Ontario are on a home therapy. Interactive health communication applications, web-based packages for patients, have been shown to have a beneficial effect on knowledge, social support, self-efficacy, and behavioral and clinical outcomes but have not been evaluated in patients with ...

Since it was introduced in 1976, continuous ambulatory peritoneal dialysis (CAPD) has won acceptance in many centres and it is now regarded as an important alternative to haemodialysis. CAPD patients have comparable and, in some circumstances, better survival than those on chronic haemodialysis. It is indicated particularly in patients with diabetes mellitus, cardiovascular instability and at t...

Abstract Background and Aims Cancer survival in the general population has improved over time. Kidney failure have a higher incidence of cancer with increased mortality. Relative following diagnosis can provide more insight into excess mortality directly or indirectly attributed to kidney population. Method We estimated compared relative for dialysis patients, transplant recipients Australia Ne...

A patient with severe thiazide-induced hyponatraemia (plasma sodium 99 mmol/l) is described, who had signs suggestive of cerebral oedema. Co-existent problems of cardiac and respiratory insufficiency were thought to make treatment with hypertonic saline hazardous. A 40-hr peritoneal dialysis successfully reversed both hyponatraemia and the associated cerebral signs, plasma sodium increasing at ...

In patients on maintenance dialysis, hyperphosphatemia is a risk factor for mortality and hospitalization. Tenapanor an investigational, first-in-class, phosphate absorption inhibitor, providing novel, non-binder approach to treating hyperphosphatemia. The PHREEDOM study was long-term Phase 3 trial evaluating the safety efficacy of tenapanor treat in dialysis (hemo- or peritoneal dialysis). Thi...